This study analysed the behaviour of both economic and financial profitability of credit unions belonging to segment 1 in Ecuador, as well as its determinants. For this purpose, data from the financial statements of a sample of 30 credit unions between 2016 and 2022 were used by means of a multiple linear regression methodology using panel data with fixed effects after applying the Hausman test. The findings of this research showed that current liquidity and non-performing loans have a negative and significant effect on both economic and financial profitability while the past due portfolio has a positive and significant impact on the generation of profitability of the financial institutions under study. In addition, it was revealed that the rate of outflow absorption has a negative relationship with economic profitability but a positive relationship with financial profitability. Unlike previous research in the Ecuadorian context, this research is pioneering in presenting results that indicate that the determinants traditionally considered for nonfinancial institutions and banks are also valid for credit unions, even though they are organisations with different characteristics from the rest.