Lighting conditions in learning spaces can affect students’ emotions and influence their performance. This research seeks to verify the influence of classroom lighting on students’ academic performance under different conditions and measurement forms. The research method is based on the systematic review of research articles establishing case analyses characterizing lighting intensity and color temperature to determine ranges favorable to a higher level of attention and long-term memory. Also, this study shows relevant aspects of the cases representative of a sustainable solution and proposes a research model. The study found light intensity values between 350 and 1000 lux and color temperatures between 4000 and 5250 Kelvin that favor attention. Long-term memory reached the highest levels of measurement by analyzing different parameters sensitive to lighting conditions and questionnaires. In conclusion, it was demonstrated that an adequate light intensity and color temperature based on the greatest possible amount of natural light complemented with Light Emitting Diode (LED) light generates optimal lighting for the classroom, achieving energy efficiency in a sustainable solution and promoting student well-being and performance.