Doping by athletes is a serious problem plaguing competitive sports around the world. Reviewing history, the traditional British endurance race is the source of doping in modern sports. Science and technology is the main driving force of social development. The competitive level of human beings has reached the height close to the limit of human potential, and it is difficult to improve sports performance by using conventional training methods, which makes athletes seek external and powerful means to improve their performance, and the achievements of natural science just meet this demand. This has also become a seemingly unavoidable phenomenon. On the one hand, this practice has been condemned by the public, on the other hand, it has become a serious problem in sports.