Artificial intelligence has triggered a global wave of the times with its breakthrough intelligent technology features such as autonomous learning ability, self-attention, and reasoning ability, which has also led to a huge change in the demand for talents in the society, and various industries are inclined to the composite innovative and high-quality talents with cross-field and multi-disciplinary backgrounds, so that the reform of higher education curriculum empowered by artificial intelligence has become an inevitable trend. It is found that although many colleges and universities have gradually opened general education and professional education on artificial intelligence, the reform of higher education curriculum still faces various problems such as monotonous teaching mode, lagging teaching content, academic ethics and morality. In order to effectively deal with these problems, this paper provides corresponding suggestions from the perspective of expecting the joint efforts and close collaboration between universities and enterprises.