The purpose of this paper is to explore the performance of ridge regression and the random forest model improved by genetic algorithm in predicting the Boston house price data set and conduct a comparative analysis. To achieve it, the data is divided into training set and test set according to the ratio of 70-30. The RidgeCV library is used to select the best regularization parameter for the Ridge regression model, and for the random forest model, the genetic algorithm is used to optimize the model's hyperparameters. The result shows that compared with ridge regression, the random forest model improved by genetic algorithm can perform better in the regression problem of Boston house prices.