The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.
This study comprehensively evaluates the system performance by considering the thermodynamic and exergy analysis of hydrogen production by the water electrolysis method. Energy inputs, hydrogen and oxygen production capacities, exergy balance, and losses of the electrolyzer system were examined in detail. In the study, most of the energy losses are due to heat losses and electrochemical conversion processes. It has also been observed that increased electrical input increases the production of hydrogen and oxygen, but after a certain point, the rate of efficiency increase slows down. According to the exergy analysis, it was determined that the largest energy input of the system was electricity, hydrogen stood out as the main product, and oxygen and exergy losses were important factors affecting the system performance. The results, in line with other studies in the literature, show that the integration of advanced materials, low-resistance electrodes, heat recovery systems, and renewable energy is critical to increasing the efficiency of electrolyzer systems and minimizing energy losses. The modeling results reveal that machine learning programs have significant potential to achieve high accuracy in electrolysis performance estimation and process view. This study aims to contribute to the production of growth generation technologies and will shed light on global and technological regional decision-making for sustainable energy policies as it expands.
Brain tumors are a primary factor causing cancer-related deaths globally, and their classification remains a significant research challenge due to the variability in tumor intensity, size, and shape, as well as the similar appearances of different tumor types. Accurate differentiation is further complicated by these factors, making diagnosis difficult even with advanced imaging techniques such as magnetic resonance imaging (MRI). Recent techniques in artificial intelligence (AI), in particular deep learning (DL), have improved the speed and accuracy of medical image analysis, but they still face challenges like overfitting and the need for large annotated datasets. This study addresses these challenges by presenting two approaches for brain tumor classification using MRI images. The first approach involves fine-tuning transfer learning cutting-edge models, including SEResNet, ConvNeXtBase, and ResNet101V2, with global average pooling 2D and dropout layers to minimize overfitting and reduce the need for extensive preprocessing. The second approach leverages the Vision Transformer (ViT), optimized with the AdamW optimizer and extensive data augmentation. Experiments on the BT-Large-4C dataset demonstrate that SEResNet achieves the highest accuracy of 97.96%, surpassing ViT’s 95.4%. These results suggest that fine-tuning and transfer learning models are more effective at addressing the challenges of overfitting and dataset limitations, ultimately outperforming the Vision Transformer and existing state-of-the-art techniques in brain tumor classification.
We studied the role of industry-academic collaboration (IAC) in the enhancement of educational opportunities and outcomes under the digital driven Industry 4.0 using research and development, the patenting of products/knowledge, curriculum development, and artificial intelligence as proxies for IAC. Relevant conceptual, theoretical, and empirical literature were reviewed to provide a background for this research. The investigator used mainly principal (primary) data from a sample of 230 respondents. The primary statistics were acquired through a questionnaire. The statistics were evaluated using the structural equation model (SEM) and Stata version 13.0 as the statistical software. The findings indicate that the direct total effect of Artificial intelligence (Aint) on educational opportunities (EduOp) is substantial (Coef. 0.2519916) and statistically significant (p < 0.05), implying that changes in Aint have a pronounced influence on EduOp. Additionally, considering the indirect effects through intermediate variables, Research and Development (Res_dev) and Product Patenting (Patenting) play crucial roles, exhibiting significant indirect effects on EduOp. Res_dev exhibits a negative indirect effect (Coef = −0.009969, p = 0.000) suggesting that increased research and development may dampen the impact of Aint on EduOp against a priori expectation while Patenting has a positive indirect effect (Coef = 0.146621, p = 0.000), indicating that innovation, as reflected by patenting, amplifies the effect of Aint on EduOp. Notably, Curriculum development (Curr_dev) demonstrates a remarkable positive indirect effect (Coef = 0.8079605, p = 0.000) underscoring the strong role of current development activities in enhancing the influence of Aint on EduOp. The study contributes to knowledge on the effective deployment of artificial intelligence, which has been shown to enhance educational opportunities and outcomes under the digital driven Industry 4.0 in the study area.
Remote sensing technologies have revolutionized forestry analysis by providing valuable information about forest ecosystems on a large scale. This review article explores the latest advancements in remote sensing tools that leverage optical, thermal, RADAR, and LiDAR data, along with state-of-the-art methods of data processing and analysis. We investigate how these tools, combined with artificial intelligence (AI) techniques and cloud-computing facilities, enhance the analytical outreach and offer new insights in the fields of remote sensing and forestry disciplines. The article aims to provide a comprehensive overview of these advancements, discuss their potential applications, and highlight the challenges and future directions. Through this examination, we demonstrate the immense potential of integrating remote sensing and AI to revolutionize forest management and conservation practices.
Cartography includes two major tasks: map making and map application, which is inextricably linked to artificial intelligence technology. The cartographic expert system experienced the intelligent expression of symbolism. After the spatial optimization decision of behaviorism intelligent expression, cartography faces the combination of deep learning under connectionism to improve the intelligent level of cartography. This paper discusses three problems about the proposition of “deep learning + cartography”. One is the consistency between the deep learning method and the map space problem solving strategy, based on gradient descent, local correlation, feature reduction and non-linear nature that answer the feasibility of the combination of “deep learning + cartography”; the second is to analyze the challenges faced by the combination of cartography from its unique disciplinary characteristics and technical environment, involving the non-standard organization of map data, professional requirements for sample establishment, the integration of geometric and geographical features, as well as the inherent spatial scale of the map; thirdly, the entry points and specific methods for integrating map making and map application into deep learning are discussed respectively.
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