The area of lake surface water is shrinking rapidly in Central Asia. We explore anthropogenic and climate factors driving this trend in Shalkar Lake, located in the Aral Sea region in Kazakhstan, Central Asia. We employ the Landsat satellite archive to map interannual changes in surface water between 1986 and 2021. The high temporal resolution of our dataset allows us to analyze the water surface data to investigate the time series of surface water change, economic and agricultural activities, and climate drivers like precipitation, evaporation, and air temperature. Toward this end, we utilize dynamic linear models (DLM). Our findings suggest that the shrinking of Shalkar Lake does not exhibit a systemic trend that could be associated with climate factors. Our empirical analysis, adopted to address local conditions, reveals that water reduction in the area is related to human interventions, particularly agricultural activities during the research period. On the other hand, the retrospectively fitted values indicate a semi-regular periodicity despite anthropogenic factors. Our results demonstrate that climate factors still play an essential role and should not be disregarded. Additionally, considering long-term climate projections in environmental impact assessment is crucial. The projected increase in temperatures and the corresponding decline in lake size highlights the need for proactive measures in managing water resources under changing climatic conditions.