This research introduces a novel framework integrating stochastic finite element analysis (FEA) with advanced circular statistical methods to optimize heat pump efficiency under material uncertainties. The proposed methodologies and optimization focus on balancing the mean efficiency and variability by adjusting the concentration parameter of the Von Mises distribution, which models directional variability in thermal conductivity. The study highlights the superiority of the Von Mises distribution in achieving more consistent and efficient thermal performance compared to the uniform distribution. We also conducted a sensitivity analysis of the parameters for further insights. The results show that optimal tuning of the concentration parameter can significantly reduce efficiency variability while maintaining a mean efficiency above the desired threshold. This demonstrates the importance of considering both stochastic effects and directional consistency in thermal systems, providing robust and reliable design strategies.

The article examines the issues of application and improvement of the methodology for evaluating industrial enterprises as recipients of state support within the framework of the implementation of industrial policy. The authors considered approaches to the content of industrial policy, investigated the factors influencing its efficiency, identified aspects of its imperfections that arise when applying an incomplete list of important parameters of economic development and ambiguity in the interpretation of previously applied estimates. The article presents proposals to improve the methodology for assessing potential recipients of state support based on the development of a comprehensive indicator for assessing enterprises (recipients of support), taking into account not only the classical parameters of the economic efficiency of industrial enterprises applying for state financial assistance, but also such aspects as the development of budgetary funds, belonging to priority sectors of the economy, characteristics of sustainable development and export and innovation potential. Combining the results of a comprehensive assessment of the recipient of state support with a map of the business demography of the territory allows making a decision not only about the fact of support and its efficiency, but also to predict the assessment of the life cycle of the enterprise and its subsequent development.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.

In Emerging economies, MNCs (Multinational corporations) encounter several issues while devising Strategies to penetrate foreign markets, examining these SMEs’ performance in present times and assessing their internationalisation process is crucial. The purpose of this research is to investigate how international entrepreneurial orientation affects SMEs’ international performance during internationalization, as well as how organizational culture in the Kingdom influences the international performance of these MNCs. To attain this objective (n = 206) MNCs in the Kingdom have adopted internationalisation strategies. Questionnaires were administered as part of a survey approach for this study. To forecast and estimate relationships, partial least squares structural equation modelling (PLS-SEM) was employed. This study indicates that improving internationalization performance, mainly through active participation in foreign markets, is one of the SMEs’ strategies during the internationalization process. The empirical findings demonstrate that international entrepreneurial orientation influences the internationalisation performance of SMEs largely influenced by organisational culture. Previous research shows that the success of SMEs’ internationalization, however, is not directly impacted by their international entrepreneurial orientation. This study supports the significance of organisational culture during internationalisation. This study offers insightful information that motivates policymakers and owner-managers in developing nations, especially in KSA, to build organizational cultures and dynamic capacities that meet the demands of globalization in today’s business scenario.

Unmanned Aerial Vehicles (UAVs) have gained spotlighted attention in the recent past and has experienced exponential advancements. This research focuses on UAV-based data acquisition and processing to generate highly accurate outputs pertaining to orthomosaic imagery, elevation, surface and terrain models. The study addresses the challenges inherent in the generation and analysis of orthomosaic images, particularly the critical need for correction and enhancement to ensure precise application in fields like detailed mapping and continuous monitoring. To achieve superior image quality and precision, the study applies advanced image processing techniques encompassing Fuzzy Logic and edge-detection techniques. The study emphasizes on the necessity of an approach for countering the loss of information while mapping the UAV deliverables. By offering insights into both the challenges and solutions related to orthomosaic image processing, this research lays the groundwork for future applications that promise to further increase the efficiency and effectiveness of UAV-based methods in geomatics, as well as in broader fields such as engineering and environmental management.