Tooth extraction of the elderly with cardiovascular disease, has drawn increasing attention of the public. In order to explore the negative effect of the extraction and reduce the potential risks helpfully, an observation was conducted in the hospital, among the elderly patients with various cardiovascular disease on their reaction towards medical monitoring in the course of the tooth extraction. The study reveals that the potential risk is relative high and the most influential risk is arrhythmia. It may be caused by the weak myocardial function and unstable emotion. Suggestions for improvements are put forward in the conclusion part.