Over 90% of cancer-related mortality worldwide is due to metastatic disease since the dynamic tumor microenvironment poses huge challenges in preventing the spread of metastatic cancer. Introducing the advent of advance biomaterials and their swift evolution, this review highlights the great potential of innovative biomaterials to proficiently tackle the metastatic tumor environment. Focusing on four distinct categories of biomaterials systems, action mechanism of biomaterials utilized in anti-tumor therapy is explained in detail: 1. Nanoplatforms sensitive to biochemical cues including pH, redox, and enzymes are known as stimuli-responsive nanoplatforms that react according their environment, 2. Smart nanoplatforms changing their morphology to penetrate impermeable physical barriers at tumor site, 3. Ingenious biomaterial participating in tumor normalization, and 4. Nanoplatforms with real-time theranostic capabilities due to innate feedback-loop mechanism. Ingeniously structured biomaterials with extensive evidence in preclinical efficacy encourage their inclusion in metastatic tumor therapy however, their utilization in medical settings is prevented due to various challenges; impractical manufacturing cost, regulatory and safety issues as well as large-scale production are major challenges restraining their widespread use. A concrete framework is proposed in this review to accelerate the biomaterial structure standardization process, following the GMP and other regulatory guidelines with the aim of implementing biomaterial-based tumor diagnostics and therapies. Since incorporating advancing technologies in tumor therapy such AI-driven, autonomous biomaterial structure or patient-specific tumor models would enable confront the proliferating metastatic tumor cases.

The activities and characteristics of heritage, cultural, and creative tourism are notably distinct despite the fact that they are frequently confused and misunderstood. Moreover, these types of tourism have been significantly affected by the COVID-19 pandemic. This review article aims to explore the characteristics of three types of tourism, both pre- and post-pandemic, and seeks to propose sustainable solutions with new opportunities for the tourism industry. The article adopts a PRISMA flow diagram and VOSviewer to perform a systematic literature review, ultimately selecting 179 articles from the Scopus, ScienceDirect, and Google Scholar databases and grouping them into five clusters: 1) heritage, cultural, and creative tourism; 2) co-creation; 3) creative city; 4) sustainability; and 5) technology and innovation. Consequently, this review article proposes a final framework presenting five related clusters suggesting sustainable solutions for creative tourism. It may aid the tourism industries in their transition to creative tourism, which is more sustainable and broadly focused while ensuring safety and enhancing income for local communities in the post-pandemic period.

The COVID-19 pandemic has significantly restricted household resilience, particularly in developing countries. The study investigates the correlation between livelihood capital and household resilience amid uncertainties due to the COVID-19 pandemic, specifically in Bekasi Regency, West Java Province, Indonesia. Livelihood capital encompasses social, human, natural, physical, and financial, which are crucial in shaping household resilience. This study used the SEM-PLS method and utilized a survey of 120 respondents (household heads) from four villages in two districts (Muaragembong and South Tambun) in Bekasi Regency to identify critical factors that either enhance or impede rural household resilience during and after the pandemic. Findings reveal that households possessing human capital, financial capital, and empowerment are more adept at navigating socioeconomic difficulties during and after the pandemic. However, this research stated that trust and social networks enhance household resilience during the pandemic, whereas social norms are crucial for rebuilding household resilience in the post-pandemic phase. The finding revealed that social cohesion adversely affected household resilience during and after the pandemic, while trust diminished household resilience in the post-pandemic COVID-19 phase. These findings offer insight to policymakers, scholars, and other stakeholders aiming to foster household resilience during and in recovery efforts after the pandemic.

Through Qualitative Comparative Analysis (QCA) on destination attractiveness characteristics at the country level, this study identifies attribute configurations in the pre- and post-pandemic period to analyze the changes and differences generated by an exogenous event (COVID-19). The results suggest that the destination attractiveness attributes work together, in multidimensional configurations, to increase leisure travel volume. We found an important change in pat-terns/configurations of attractiveness between the pre- and post-pandemic scenarios. Our findings suggest that the destination attributes may change in importance and valuation or disappear for some configurations. The conclusion has implications for the stakeholders related to the destination attractiveness development, showing possible patterns of tourism attributes to guide the action to improve the resilience in the tourism sector and recover these activities in a disaster scenario.

The COVID-19 pandemic provided a unique opportunity for educators and policymakers to reconsider education systems and rethink what is essential, necessary, and desirable for future generations. A sequential generic qualitative approach was used in this study. Based on the systematic literature review, a content analysis was conducted to identify dimensions that contribute toward higher education institutions sustainability. Subsequently, the Expert Opinion method that involved five professors holding key positions in respective universities from Malaysia, the Netherlands, India, and Bangladesh was applied to propose a post-COVID-19 sustainable framework. Four themes: 1) educational reform; 2) digital transformation; 3) resilience and change management; and 4) sustainability coupled with agility and flexibility formed the framework for HEIs’ sustainability during the post-COVID-19 pandemic. We propose that the themes be examined from an integrated perspective to ensure HEIs can be sustainable in the long run. Finally, other scholars are recommended to conduct a tracer study as well as develop qualitative instruments based on the themes and dimensions identified from the systematic literature review and the Expert Opinion Method to better understand the phenomenon of HEI sustainability.

Rapid urban expansion gives rise to smart cities which pose immense logistical and supply chain challenges. The COVID-19 pandemic transformed the holistic system identified by Zhao et al. in 2021. The system encompasses logistics and supply chain integral to the concept of smart cities, with a focus on sustainability. This transformation requires an in-depth study on challenges of a common framework of policies for smart cities in countries comprising the Organisation for Economic Cooperation and Development (OECD). The study employs an extensive literature analysis for the period 2020–2022. an approach which contextualizes the model. The model identifies the causes, impact, and spillovers of new trends in logistics and supply, including the sustainability of adopted technologies. The study includes the variables involved, and barriers to creating a shared model. The results reveal that the two elements affecting the supply chain and transport in smart cities are Industry 4.0 and 5.0 technologies supporting specific sectors. The resilience of small and medium-sized enterprises positively impacts the sustainability of large urban centres. The study presents both factors that help and hinder the adoption of environmental, social, and economic sustainability technologies.