Clinical/methodological problem: The identification of clinically significant prostate carcinomas while avoiding overdiagnosis of low-malignant tumors is a challenge in routine clinical practice. Standard radiologic procedures: Multiparametric magnetic resonance imaging (MRI) of the prostate acquired and interpreted according to PI-RADS (Prostate Imaging Reporting and Data System Guidelines) is accepted as a clinical standard among urologists and radiologists. Methodological innovations: The PI-RADS guidelines have been newly updated to version 2.1 and, in addition to more precise technical requirements, include individual changes in lesion assessment. Performance: The PI-RADS guidelines have become crucial in the standardization of multiparametric MRI of the prostate and provide templates for structured reporting, facilitating communication with the referring physician. Evaluation: The guidelines, now updated to version 2.1, represent a refinement of the widely used version 2.0. Many aspects of reporting have been clarified, but some previously known limitations remain and require further improvement of the guidelines in future versions.

The relationship between transport infrastructure and accessibility has long stood as a central research area in regional and transport economics. Often invoked by governments to justify large public spending on infrastructure, the study of this relationship has led to conflicting arguments on the role that transport plays in productivity. This paper expands the existing body of knowledge by adopting a spatial analysis (with spillover effects) that considers the physical effects of investment in terms of accessibility (using distinct metrics). The authors have used the Portuguese experience at regional level over the last 30 years as a case study. The main conclusions are as follows: i) the choice of transport variables matters when explaining productivity, and more complex accessibility indicators are more correlated with; ii) it is important to account for spill-over effects; and iii) the evidence of granger causality is not widespread but depends on the regions.

The women’s sector in the academe is one of the most affected profiles during the COVID-19 pandemic which directly ravages their livelihood and other economic activities. Thus, this research project investigated the economic situations of 30 private and public-school teachers who were displaced from their occupations or were forcibly deprived of income-generating activities. In-depth interviews as research instruments were employed in the study to extract responses on how the educators creatively apply adaptive economic strategies and how government should aid them during a global crisis. The research findings showed that the pandemic has affected the economic activities of the respondents including the loss of their livelihood and other economic sidelines. They responded to these economic effects through adaptive strategies using diversifying and analyzing trends, using digital technology resources, data-driven, acquiring new alternative skills, pricing strategy, and becoming an expert. Results dictated that government could support affected women by initiating training options, homepreneurship support, encouraging independent income-earners, financial management and tax breaks, and industry compatibility endorsement. This study is important to map out the specific economic effects of the pandemic and aid them with initiatives by providing them with concrete economic tools and programs.

Gold nanoparticles (AuNPs) have been known to possess exceptional electric, biochemical, and optical characteristics and are ‘the topic of discussion’ these days, especially relating to the field of biomedicine. Several plants, bacteria, and fungi have been utilized for the generation of AuNPs, besides other physical and chemical methods. While some studies have been reported with gold nanoparticles, less are aimed at fungi and its optimization factors. These parameters can allow us to design AuNPs of our choice depending on the use. The present review focuses on and inspects AuNPs with green synthesis through fungus optimization parameters followed by applications, aiming specifically at their antibacterial activity. Their antibacterial characteristics can open new doors for the pharmaceutical industry in the future.

The mining industry significantly impacts the three pillars of sustainable development: the economy, the environment, and society. Therefore, it is essential to incorporate sustainability principles into operational practices. Organizations can accomplish this through knowledge management activities and diverse knowledge resources. A study of 300 employees from two of the largest mining corporations in South Kalimantan, Indonesia, found that four out of five elements of knowledge management—green knowledge acquisition, green knowledge storage, green knowledge application, and green knowledge creation—have a direct impact on the sustainability of businesses. The calculation was determined using Structural Equation Modelling (SEM). However, the study also found that the influence of collectivist cultural norms inhibits the direct effect of green knowledge sharing on corporate sustainable development. The finding suggests that companies operating in collectivist cultures may need to take additional measures to encourage knowledge sharing, such as rewarding employees for sharing their expertise on green initiatives, supportive organizational culture, clear expectations, and opportunities for social interaction.

Workplace bullying (WB) and workplace incivility (WI) appear to be the most alarming events with a potentially threat to the entire workforce and organization. Considering their implications, this research study is examining the effect of WB and WI on employee performance (EP) in the presence of psychological well-being (PW) among both relationships. Sample of the female employees (Nurses) working in the health care units and hospitals of the Azad Jammu and Kashmir (AJ&K), Pakistan was taken to collect the data. Data were collected from female nurses and their supervisors working in the public sector hospitals of AJ&K, Pakistan. The current study uses AMOS 21.0 for empirical analysis to estimate the “Structural Equation Model (SEM)”. The results of SEM show that WB and WI negatively influence nurses’ performance in Azad Jammu and Kashmir’s health sectors. Moreover, PW mediates the association between WB and EP. Similarly, the effects of WI decrease in the presence of PW. The current study provides theoretical and practical implications for Pakistan’s health sector regulators and other stakeholders. It also sheds highlight on the importance of a stress-free environment for health sector employees and postulates that employee productivity may be enhanced after eliminating bullying and incivility at the workplace. Further, the study guides managers to create stress-free environments and policies to enhance employee’s productivity.