The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.

In the era of digital disruption, the imperative development of broadband services is evident. The emergence of 5G technology represents the latest stride in commercial broadband, offering data speeds poised to drive significant societal advancement. The midst of responding to this transformative phenomenon. This pursuit unveils a landscape replete with opportunities and challenges, particularly regarding how 5G’s potential benefits can drive the government towards equitable distribution, ensuring accessibility for all. Simultaneously, there exists a legal hurdle to ensure this vision’s fruition. From a legal perspective, perceived as infrastructure for transformation, the law must seamlessly adapt to and promptly address technological progress. Utilizing normative juridical methods and analytical techniques via literature review, this research endeavors to outline the advantages of 5G and scrutinize Indonesia’s latest telecommunications regulations and policies, alongside corresponding investments. The study ultimately aims to provide a juridical analysis of 5G implementation within Indonesia’s legal framework.

The rise of internet-based pharmacies has transformed the healthcare sector, giving patients access to medications, information, and direct interaction with pharmacists. While online pharmacies have become popular around the world, there are challenges hindering their widespread use in developing countries due to a limited understanding of the factors affecting their acceptance and usage. To bridge this knowledge gap, a study utilized a model combining the unified theory of acceptance and use of technology (UTAUT 2) with the technology acceptance model (TAM) to explore the drivers behind online pharmacy usage in Oman. Through this framework, twelve hypotheses were. A survey involving 378 individuals familiar with online pharmacies was conducted. Structural equation modeling (SEM) was applied to analyze the data and test these hypotheses. The results indicate that factors such as perceived expectancy effort expectancy and facilitating conditions hedonic motivation, habit perceived risk, technology trust, and technology awareness play roles in influencing the adoption of online pharmacies in Oman. The findings suggest that personal innovation plays a moderating role in the connection between perceived risk and behavioral intention, while it has a negative moderating influence on the relationship between technology trust and behavioral intention. Word of mouth was identified as a moderator in enhancing the correlation between behavioral intention and online pharmacy adoption. This research emphasizes the moderating relationship of personal innovation and word of mouth on shaping consumer attitudes towards online pharmacies and their acceptance. In summary, these results add to the existing knowledge on pharmacy adoption and in developed areas such as provide practical insights for online pharmacy providers to improve their offerings and attract a larger customer base.

The ultimate objective of the study was to investigate the effects of being landlocked on the living standards in Sub-Saharan African (SSA) countries from 1991 to 2019. Adopting the two-step estimation technique of System GMM (generalized method of moments), the study found that being landlocked has a negative and significant effect on the living standards in SSA countries when using GDP per capita as the living standard measure. Moreover, the historical living standard experiences of SSA countries have a positive and significant influence on the current living standard level. In addition, the population growth rate has a positive and significant effect on the living standards in SSA countries. On the other hand, the official exchange rate, broad money as a percentage of GDP, and inflation have a negative and significant effect on the living standards in SSA countries. Generally, the estimated result reveals the existence of a significant variation in the living standards in landlocked and coastal SSA countries. This study suggests that regional integration between landlocked and transit countries should be improved to minimize entry costs and increase access to global markets for landlocked countries. We argue that this study is of interest to landlocked and coastal countries to increase trade integration and promote the development of both groups, and it will contribute to the scarce empirical evidence.

Personality traits refer to enduring patterns of emotions, behaviors, and thoughts that shape an individual’s distinct character, influencing how they perceive and engage with their environment. This quantitative study aims to underscore the influence of personal factors and the role of educational institutions in mapping sustainable green entrepreneurial intentions among university students in Saudia Arabia. To examine the impact of personality traits and entrepreneurship education on students’ green initiatives, the research employs a quantitative research method, collecting data through a structured questionnaire survey from 494 participants who enrolled in the entrepreneurship education at King Faisal University. Structural equation modeling via SmartPLS 3 is employed for data analysis. The study reveals significant associations between the need for achievement, proactiveness, risk-aversion, self-efficacy, and entrepreneurship education with green entrepreneurial intentions. Our research findings demonstrate that the inclusion of entrepreneurship education in the curriculum has a noteworthy and favorable influence on the intention to engage in green entrepreneurship (β = −0.105, t = 3.270, p < 0.001). Additionally, it is worth noting that the desire for achievement remains significantly associated with the intention to engage in green entrepreneurship (β = 0.120, t = 3.588, p < 0.000). Furthermore, the proactive behavior of individuals has a positive and constructive impact on the intention to engage in green entrepreneurship (β = 0.207, t = 4.272, p < 0.000). Similarly, the inclination to avoid risk is found to have a beneficial and significant influence on the intention to engage in green entrepreneurship (β = 0.336, t = 4.594, p < 0.000). Lastly, it is worth highlighting that individuals’ belief in their own abilities, referred to as self-efficacy, is positively and significantly linked to the intention to engage in green entrepreneurship (β = 0.182, t = 2.610, p < 0.009). The research carries social, economic, and academic implications by emphasizing the positive contribution of green entrepreneurs to the future. Practical recommendations for policymakers and decision-makers are provided.