In response to the new requirements of the “1333” goal, which is the target of the new engineering construction, and closely centered around the educational focus of “Information Industry Business School” and the training goal of “high-quality application-oriented talents serving the information industry”, in order to effectively improve the teaching of “Electrical Control and Programmable Logic Controller” and make the course objectives closer to the talent training objectives of electrical engineering and meet the needs of social and industrial development, we have carried out research on teaching reform and practice, deepened the reform of course teaching, analyzed the current situation of the teaching of this course in detail, and put forward the “four-wheel drive” reform plan for the teaching reform of this course. Practice has proved that the teaching reform of this course has achieved significant results, and students’ comprehensive ability has been significantly improved. This reform and practice are of great significance for improving the quality of applied undergraduate talent training, keeping up with social development trends, demonstrating school characteristics and achievements in educating people, and showing school characteristics and achievements in educating people.