The possibility of preoperative prediction of pathologic complete response in rectal cancer has been studied in order to identify patients who would respond to neoadjuvant therapy and to individualize therapeutic strategies. Endoscopic ultrasound of the rectum is an accurate method for the evaluation of local tumor and lymph node invasion. Objective: To evaluate the potential of endoscopic ultrasound as a predictor of complete pathological response to neoadjuvant treatment in patients with locally advanced rectal cancer. Material and methods: Retrospective study of patients with rectal cancer from January 2014 to December 2016. Results: We obtained a statistical association between T stage by endoscopic ultrasound and complete pathological response (p = 0.015). It is not so for N, sphincter involvement, circumferential involvement and maximum tumor thickness (p = 0.723, p = 0.510, p = 0.233 and p = 0.114, respectively). When multivariate logistic regression analysis was applied to assess the degree of influence of the predictor variables on pathologic response, none of these variables was associated with complete pathologic response. Conclusion: Prediction of pathologic complete response in rectal cancer has been considered as the crucial point upon which treatments for rectal cancer could be individualized. So far, no imaging method has been able to demonstrate efficacy in predicting complete pathologic response, and in turn there is no direct association between any endosonographic finding that can accurately predict it.

Objective: To evaluate the ponticulus posticus according to the skeletal relationship found in strict lateral radiographs at the Centro Dental Docente of the Universidad Peruana Cayetano Heredia during the period 2015–2017, using the classification according to the degree of mineralization described by Selby and Steiner’s skeletal relationship classification. Material and methods: It was performed on digital strict lateral radiographs using a 20-inch screen using the SIDEXIS XG program, observing the degree of mineralization of the ponticulus posticus: without evidence of the bony spicule over the vertebral artery = absent bridge, when spicule formation and/or calcification was noted or evident in the middle of the bridge or incompletely = partial bridge, when the bony arch was evident finished visualizing = complete bridge and the classification of the skeletal relationship by measuring the ANB angle: Class I = 0–4°; Class II = >4° and Class III = <0°: the statistical analysis was done with the SPSS V program.22.0 for Windows using the Chi-square tests. Results: Of the 925 digital strict lateral radiographs evaluated, 283 radiographs were found to present ponticulus posticus and the highest frequency was found in the absent type (69.4%), the partial type (17.1%) and the complete type (13.5%). The ponticulus posticus was present in 25.1% of the female and 38.4% of the male. The skeletal relationship associated with ponticulus posticus was present in Class II (19.1%), Class I (10.4%) and Class III (1.1%). Conclusions: The ponticulus posticus is an anatomical variant present in 30.6% of cases. No statistically significant difference was found between the presence of ponticulus posticus and skeletal relationship or sex.

In this paper, all the forests, woodlands and trees in the administrative area of Zhaoling Township in Chuzhou City of Huai'an City were collected and analyzed. The total area of the administrative area is 4852 hectares, the forest coverage rate is 22.07%, and the forest greening rate is 26.13%. This index has exceeded 20% of the forest coverage rate of the well - off society. Tree species is particularly serious. In the forest system (pure forest), the area of pure forest of poplar is accounted for 99.9% of the whole forest area. In the four tree systems, the number of poplar trees accounted for 80% of the total number of trees in the whole tree, and the total amount of poplar trees accounted for 98%. The poplar pure forest age group structure disorders, the unit area is low. The ratio of total area of poplar pure forest in Zhongling and young forests was 92.9%, and the ratio of total area of poplar pure forest and mature forest was 7.1%. The ratio of mature forest and the ratio of mature forest was 0.7%, and the proportion of each group was obviously abnormal.

Ebola virus is a potent infectious disease virus that can cause Ebola haemorrhagic fever caused by human and primate. It has high mortality and easy infectivity to form a great obstacle to the steady development of human society. The profound understanding of the virus is particularly important harm. In this paper, a number of mathematical models are established to solve this problem. The software is used to analyze and predict the propagation of Ebola virus. The residual analysis is used to test the model. Finally, the effects of various control measures on controlling the epidemic are analyzed. In order to solve the problem, we will establish the infectious disease model to dynamically describe the spread of the virus in the 'virtual orangutan population'. Considering that the latent population is analyzed in this question, we will improve the model. Join the latent group (), and the migrants are divided into self-healing () and the dead (), to establish a suitable solution to this problem model. According to the relevant data given in the title, differential equations were established. For the second question, this question involves the one-way transmission of the virus across the species, so we can improve the model, on the basis of human contact with orangutans infected groups, the establishment of a one-way model to solve this problem. On the basis of the problem one, the differential equation is established, the model is predicted and tested. In the case of question 3, the number of human susceptible groups is much higher than that of the orangutan infection group by comparing the relevant data with the increase of the cure rate to 80% after the intervention of the outside experts. Therefore, the original data of human populations from experts can be ignored. Since then the virus spreads within a single species, the differential equation can be established according to the model in question 1 and the data values in the virtual human population are predicted. For question 4, the effect of the measures such as the strict enforcement of the various epidemic control measures and the improvement of the drug effect on the control of the epidemic are analyzed by comparing the above-mentioned models with the control measures.

The Belt and Road Initiative (BRI) aims to enhance connectivity and collaboration among 60 countries and beyond in Asia, Africa and Europe. Information and communications technology (ICT) is an indispensable component of the initiative, critical in providing fundamental communication channels for global financial transactions, trade exchanges and transport and energy connectivity, and socio cultural collaboration and scientific exchanges between people, organizations and countries along the BRI corridors. Previously constrained by infrastructure deficits in ICT, the Asia-Pacific region is accelerating its efforts to provide reliable and affordable broadband networks throughout the region, to contribute to successful implementation of the Sustainable Development Goals (SDG).

Within the BRI corridors, this study which has been undertaken as part of the research programme of the United Nations Economic and Social Commission for Asia and the Pacific (ESCAP) on promoting regional economic cooperation and integration, focuses on the China-Central Asia Corridor (China, Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan and Uzbekistan), giving attention to the sub-region’s specific challenges, namely limited international transit opportunities and an increase in bandwidth requirements that is expected to grow exponentially, as the fourth industrial evolution centered on automation and artificial intelligence gathers momentum. The sub-region is characterized as highly dependent on the ease and costs of connecting to neighboring countries for transit, as many countries in the sub-region are landlocked developing countries (LLDC). Because of the geographical features and other factors, the development potential of Central Asia and its integration into globalization, continues to be stymied by insufficient international bandwidth and high transit costs to access international links. Therefore, improved ICT connectivity in Central Asia through the BRI corridor could result in improved availability and affordability of broadband networks and services in the sub-region.

For the purpose of this study, a gap analysis is the methodology that underpins the proposed topology for the China-Central Asia Corridor. The analysis included examining the current state of the optic infrastructure, such as existing and planned fiber-optic networks, existing Internet Exchange Points (IXPs) and international gateways. The study also identifies the key factors that determine the desired future state of infrastructure deployment for the BRI initiative. A topology that consists of connecting Almaty (Kazakhstan) and Urumqi (China), as core nodes, is proposed based on a partial mesh topology. Over and above this core finding, the study concludes that digital infrastructure connectivity has a tendency of lagging behind the rapid opportunities evolving, and the study therefore advocates for sub-regional and regional approaches, including the BRI and Asia-Pacific Information Superhighway (AP-IS) in further expanding regional broadband networks. A key recommendation of the study is co-deployment of broadband infrastructure along passive infrastructure, as an additional cost effective means of achieving fast and affordable broadband connectivity for all.

A large number of people of the fringe areas of Sundarban enter into the forests every year and encounter with the tigers simply for their livelihood. This study attempts to examine the extent and impact of human-animal conflicts in the Sundarban Reserve Forest (SRF) area in West Bengal, India. An intensive study of the data of the victims (both death and injury) between 1999 and 2014 reveals that, fishermen crab collector, honey collectors and woodcutters are generally victimized by the tiger attack. Pre monsoon period (April to June) and early winter period (Jan to March) are noted for the two-peak periods for casualties. Maximum casualty occurs between 8-10 am, and 2-4 pm. Jhilla (21.1%), Pirkhali (19.72 %), Chandkhali (11.72%), and Arbesi (9.35%) are the four most vulnerable forest blocks accounting more than 60 per cent occurrence of incidences. 67.24 per cent of the tiger attack victims were residents of Gosaba followed by Hingalganja (15%) and Basanti, (9.76%). The vulnerability rating puts the risk of tiger attack to 0.88 for every 10,000 residents of Gosaba block followed by 0.33 at Hingalganj Block and 0.11 at Bansanti Block. The majority of the victims (68%) were found to be males, aged between 30 and 50 years.