As a bridge for human interaction with the outside world, clothing design must not only meet the basic functional needs but also be able to trigger and satisfy people’s emotional needs. From the perspective of emotional expression, the emotional experience in clothing design can enhance consumers’ emotional value, thereby increasing the added value of clothing. This illustrates the importance of considering the five senses in fashion design. The objective of this paper is to analyze the significance of the five senses to fashion designers and to investigate the influence of the five senses on cutting-edge fashion design.