Adolescent childbearing is a crucial problem challenging policymakers in sub-Saharan African countries. The objective of this study is to show how teenage pregnancy and motherhood is related to social determinants like place of residence, education level and wealth quintiles, and consequently to suggest pragmatic actions susceptible to control the burden of teenage pregnancy. Disaggregated data were analyzed using data covering the decade 2012–2022 and provided by Demographic Health Surveys. In each country considered, the index of dissimilarity (ID) was computed to illustrate the variation of teenage pregnancy and motherhood according to the level of education, the rural-urban residence and the income quintiles. Recent statistics were also used for a comparison between countries. This study showed that childbearing affected 22.7% of African adolescents (15–19 years). However, the rate of adolescent childbearing varied from 40.4% in Nigeria to 5.2% in Ruanda. Moreover, huge differences were found in each country. Teenage girls living in rural areas, illiterate or with low level of education and suffering from poverty are more likely to be early married and to be exposed to pregnancy. The rate of adolescent childbearing is higher in Sub-Saharan African countries compared with countries from Latin America and World Health Organization Eastern Mediterranean. Most of the 31 countries considered in this study suffer from high rate of adolescent childbearing and large iniquities by place of residence and/or education level and/or wealth quintiles. Consequently, policymakers should adopt urgent and efficient strategies to reduce (and ideally to end) early marriage and teenage pregnancy by developing a policy that targets disadvantaged girls living in remote areas, having low or no decent income and suffering from illiteracy or low level of education.