Sustainable innovation is crucial for addressing social and environmental challenges and is a key driver of enterprise competitiveness and economic growth. This study examines how board heterogeneity influences sustainable innovation in enterprises, particularly within the context of China’s Science and Technology innovation board. Findings reveal that diverse boards enhance sustainable innovation and impact M&A activities, which in turn mediate the relationship between board diversity and corporate sustainability. The research aims to understand the optimal board composition for scientific and creative enterprises, analyze the mechanisms behind board heterogeneity’s effect on innovation, and assess M&A’s role in this process. The study’s outcomes underscore the importance of board diversity for fostering sustainable innovation and suggest that M&A can be a critical pathway to enhancing corporate sustainability.