The development and expansion of economies depend heavily on entrepreneurship, and Malaysia is no exception. Understanding the underlying elements that impact the success or failure of user adoption behaviour of online shopping activities is significant since entrepreneurship is critical in driving economic growth and innovation. The study includes 73 articles published from 2004 to the last of 2023 from Science Direct, Scopus, Google Scholar, and Web of Science. We utilised qualitative methods and systematic review issues through the findings of “qualitative” studies as the last step inside a systematic review using Nvivo14. Our study’s result illustrated that applying the Technology Acceptance Model (TAM) and the Unified Theory of Acceptance and Use of Technology (UTAUT) in Malaysian e-commerce validates the relevance of established theoretical frameworks. This study explores the relationship between 20 independent variables and five mediator factors, with dependent variables, e-commerce in Malaysia. The results highlight the intricate relationships between these variables and their importance for companies, decision-makers, and other stakeholders involved in Malaysian infrastructure financing. This review provides legislators, educators, researchers, and businesspeople with new knowledge in Malaysia so that decision-makers, investors, and aspiring entrepreneurs can make informed decisions.