Researchers from all over the world have been working tirelessly to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic since the World Health Organization (WHO) proclaimed it to be a pandemic in 2019. Expanding testing capacities, creating efficient medications, and creating safe and efficient COVID-19 (SARS CoV-2) vaccinations that provide the human body with long-lasting protection are a few tactics that need to be investigated. In clinical studies, drug delivery techniques, including nanoparticles, have been used since the early 1990s. Since then, as technology has advanced and the need for improved medication delivery has increased, the field of nanomedicine has recently seen significant development. PNPs, or polymeric nanoparticles, are solid particles or particulate dispersions that range in size from 10 to 1000 nm, and their ability to efficiently deliver therapeutics to specific targets makes them ideal drug carriers. This review article discusses the many polymeric nanoparticle (PNP) platforms developed to counteract the recent COVID-19 pandemic-related severe acute respiratory syndrome coronavirus (SARS-CoV-2). The primary subjects of this article are the size, shape, cytotoxicity, and release mechanism of each nanoparticle. The two kinds of preparation methods in the synthesis of polymeric nanoparticles have been discussed: the first group uses premade polymers, while the other group depends on the direct polymerization of monomers. A few of the PNPs that have been utilized to combat previous viral outbreaks against SARS-CoV-2 are also covered.
A large number of people of the fringe areas of Sundarban enter into the forests every year and encounter with the tigers simply for their livelihood. This study attempts to examine the extent and impact of human-animal conflicts in the Sundarban Reserve Forest (SRF) area in West Bengal, India. An intensive study of the data of the victims (both death and injury) between 1999 and 2014 reveals that, fishermen crab collector, honey collectors and woodcutters are generally victimized by the tiger attack. Pre monsoon period (April to June) and early winter period (Jan to March) are noted for the two-peak periods for casualties. Maximum casualty occurs between 8-10 am, and 2-4 pm. Jhilla (21.1%), Pirkhali (19.72 %), Chandkhali (11.72%), and Arbesi (9.35%) are the four most vulnerable forest blocks accounting more than 60 per cent occurrence of incidences. 67.24 per cent of the tiger attack victims were residents of Gosaba followed by Hingalganja (15%) and Basanti, (9.76%). The vulnerability rating puts the risk of tiger attack to 0.88 for every 10,000 residents of Gosaba block followed by 0.33 at Hingalganj Block and 0.11 at Bansanti Block. The majority of the victims (68%) were found to be males, aged between 30 and 50 years.
In an effort to bridge the gap of economic and social inequality among the community, rural areas in Indonesia are encouraged to be self-sufficient in generating income. This makes the central government create various policies so that the regional government maximizes the management of its potential as an economic resource for the well-being of its people. One of the ways to manage this potential is to encourage rural areas to create tourism products that can be sold to the public. The Indonesian governments openly use the tourism sector as a tool for the development in many rural areas. Next, efforts to achieve successful development of the district will be closely related to the strategic planning and long-term cooperation of each local government with stakeholders in its implementation. These two points are the basic elements of the new regionalism theory. This theory states that the role of local governments is very important in initiating and making policies for new economic activities for a significant improvement in the quality of their population. Therefore, this study tries to explore how the new theory of regionalism can include rural development from a tourism perspective as a way to stimulate the fading economy in rural area of Indonesia. The study found that the new theory of regionalism needs support from various aspects such as social-cultural, community participation, the three pillars of sustainable development namely economic, social, and environmental as well as basic aspects to shape sustainable rural development through tourism.
Transitioning to a green economy is a global concern, considered a pathway to sustainable development. This paper aims to investigate the effect of the transition into a green economy on Vietnam’s sustainable development and its two economic and environmental dimensions, with consideration of several essential issues including renewable energy, technological innovation, natural resource rents (oils, forest, and minerals), foreign direct investment, and trade. This paper utilizes data from 1996 to 2020 and then applies the autoregressive distributed lag (ARDL) method for analysis. The results conclude that renewable energy is a driving key to reducing environmental degradation, but it hampers economic growth, while the contrast occurs with technology. Our results emphasize the dependence on non-renewable energy, whereas the innovation of technology does not show a green orientation in Vietnam. Furthermore, there is a lack of sustainability in the effect of natural resource rents, foreign direct investment, and trade. Overall, the transition into a green economy in Vietnam does not illustrate the sustainable orientation. The findings of this research provide empirical evidence to clarify the relationship between this transition and its driving factor, with sustainable development and the two economic environment dimensions. In addition, this study will bring worthwhile implications for the policymakers and scholars on whether the transition to a green economy fulfills the orientation towards sustainability, then enhancing the economy's efficiency to achieve green growth, following the pathway to sustainable development.
The global shortage of nurses has resulted in the demand for their services across different jurisdictions causing migration from developing to developed regions. This study aimed to review the literature on drivers of nurses’ migration intentions from source countries and offer future research directions. A search strategy was applied to ScienceDirect, Web of Science, and Scopus academic databases to find literature. The search was limited to peer-reviewed, empirical studies published in English from 2013–2023 resulting in 841 papers. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to conduct a systematic review of 35 studies after thorough inclusion and exclusion criteria. In addition, the VOSviewer software was utilized to map network visualization of keywords, geographic and author cooperation for bibliometric understanding. The findings revealed various socio-economic, organizational, and national factors driving nurses’ migration intentions. However, limited studies have been conducted on family income, organizational culture, leadership style, infrastructure development, social benefits, emergency service delivery, specialized training, and bilateral agreements as potential drivers for informing nurses’ migration intentions. Moreover, a few studies were examined from a theoretical perspective, mainly the push and pull theory of migration. This paper contributes to the health human resources literature and shows the need for future studies to consider the gaps identified in the management and policy direction of nurse labor migration.
The ongoing railway reforms in Ukraine are crucial for the country’s integration into the European Union’s transportation network. A major challenge lies in the difference in track gauge widths: Ukraine predominantly uses a 1520 mm gauge, while European countries utilize a 1435 mm gauge. This 85 mm difference presents significant logistical and operational barriers, hindering smooth cross-border trade and travel. The study examines the current state of Ukraine’s railway system, highlighting the urgent need for infrastructure modernization to meet European standards. Methods include a comparative analysis of Ukraine’s railway network with those of EU member states, focusing on integration challenges and potential solutions. Results indicate that aligning Ukraine’s railway with European standards could substantially enhance connectivity, reduce transit times, and foster economic growth. However, “Ukrzaliznytsia’s” slow adaptation to these necessary changes is a major roadblock. The study concludes that the construction of a standard-gauge railway linking Ukraine to the EU is vital not only for improving trade routes but also for supporting Ukraine’s broader political and economic aspirations towards EU membership. Circular economy principles, such as resource optimisation, extending the life cycle of existing infrastructure and reusing materials from dismantled railway facilities, can offer a cost-effective and sustainable approach. This infrastructural change will serve as a catalyst for deeper integration, strengthening Ukraine’s position within the European transportation network.
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