Objective: To describe magnetic resonance imaging (MRI) findings of the brain in patients younger than 65 years who were studied by transcranial Doppler (TCD) with microbubble contrast, with a history of cryptogenic cerebrovascular accident (CVA) and suspected patent foramen ovale (PFO).

Materials and methods: This retrospective cross-sectional study included patients of both sexes, younger than 65 years of age.

Results: Our sample (n = 47.47% male and 53% female, mean age is 42 years) presented high-intensity transient signals (HITS) positive in 61.7% and HITS-negative in 38.3%. In HITS-positive patients, lesions at the level of the subcortical U-brains, single or multiple with bilaterally symmetrical distribution, predominated. In patients with moderate HITS, lesions in the vascular territory of the posterior circulation predominated.

Conclusion: In patients younger than 65 years with cryptogenic stroke and subcortical, single or multiple U-shaped lesions with bilateral and symmetrical distribution, a PFO should be considered as a possible cause of these lesions.

This research delves into the correlation between institutional quality and tourism development in a panel of nine Mediterranean countries within the European Union spanning from 1996 to 2021. The study gauges tourism development by examining tourist arrivals, while considering GDP growth rate, inflation, higher education, environmental quality, and trade as control variables representing factors influencing tourism. Institutional quality is measured through indicators such as regulatory quality, rule of law, and control of corruption. Utilizing Fully Modified Ordinary Least Square (FMOLS) and Dynamic Ordinary Least Squares (DOLS) models, the study aims to quantify the impact of these factors on tourism development. The findings indicate a positive relationship between institutional quality and tourism, shedding light on the pivotal role of institutions in tourism management and their influence on the sector. These results have implications for shaping national development strategies.

The significance of remittances to the Vietnamese economy necessitates investigating how they affect the value of the Vietnamese currency and other macroeconomic factors. Macroeconomic articles struggle to discover their impact on economic development, but measured remittances by migrant workers have recently soared. There is no academic study that has examined this phenomenon in Vietnam. This study uses wavelet frameworks to analyze the lead-lag nexus between exchange rates, remittances, and economic growth in Vietnam in time-frequency domains from 1995 to 2020. Overall, we find that: (i) remittances enhance economic growth in the short and medium run; (ii) exchange rates boost remittances in the short and medium run; (iii) exchange rates promote GDP in all frequency and time domains. Moreover, the partial wavelet coherence and multiple wavelet coherence frameworks also offered evidence supporting the wavelet coherence approach. More importantly, the outcomes of wavelet-based Granger causality unveil that there is two-way causality between the selected indicators, which means that all the indicators can predict each other at different frequencies. Our empirical results provide meaningful information for market participants and policymakers.

This study explores the spatial distribution pattern of educational infrastructure development across districts and cities in North Sumatra, identifying significant disparities between urban and rural areas. The study aims to: (1) determine the distribution of educational development across districts and cities, (2) analyze global spatial autocorrelation, and (3) identify priority locations for educational development policies in North Sumatra Province. The methodology includes quantile analysis, Moran’s Global Index, and Local Indicators of Spatial Autocorrelation (LISA) using GeoDa software to address spatial autocorrelation. The results indicate that there are nine areas with a low School Participation Rate Index (SPRI), eleven areas with a low School Facilities and Infrastructure Index (SFII), and eleven areas with a low Regional Education Index (REI). Spatial autocorrelation analysis reveals that SFII shows positive spatial autocorrelation, while SPRI and REI exhibit negative spatial autocorrelation, indicating a high level of inequality between regions. Labuhan Batu Selatan and Labuhan Batu are identified as priorities for the provincial government in overseeing educational development policies.