Amyloidosis is a systemic disorder produced by the deposition of insoluble protein fibrils that fold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality than patients without cardiac involvement. The two most prevalent forms of amyloidosis associated with cardiac involvement are AL amyloidosis, due to the deposition of immunoglobulin light chains, and ATTR amyloidosis, due to the deposition of the transthyretin (TTR) protein in mutated or senile form. This article aims to review the different cardiac imaging modalities (echocardiography, cardiac magnetic resonance imaging, nuclear medicine and tomography) that allow to determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, we suggest a diagnostic algorithm to determine cardiac involvement in amyloidosis adapted to locally available diagnostic tools, with a practical and clinical approach.
Quantum dot can be seen as an amazing nanotechnological discovery, including inorganic semiconducting nanodots as well as carbon nanodots, like graphene quantum dots. Unlike pristine graphene nanosheet having two dimensional nanostructure, graphene quantum dot is a zero dimensional nanoentity having superior aspect ratio, surface properties, edge effects, and quantum confinement characters. To enhance valuable physical properties and potential prospects of graphene quantum dots, various high-performance nanocomposite nanostructures have been developed using polymeric matrices. In this concern, noteworthy combinations of graphene quantum dots have been reported for a number of thermoplastic polymers, like polystyrene, polyurethane, poly(vinylidene fluoride), poly(methyl methacrylate), poly(vinyl alcohol), and so on. Due to nanostructural compatibility, dispersal, and interfacial aspects, thermoplastics/graphene quantum dot nanocomposites depicted unique microstructure and technically reliable electrical/thermal conductivity, mechanical/heat strength, and countless other physical properties. Precisely speaking, thermoplastic polymer/graphene quantum dot nanocomposites have been reported in the literature for momentous applications in electromagnetic interference shielding, memory devices, florescent diodes, solar cells photocatalysts for environmental remediation, florescent sensors, antibacterial, and bioimaging. To the point, this review article offers an all inclusive and valuable literature compilation of thermoplastic polymer/graphene quantum dot nanocomposites (including design, property, and applied aspects) for field scientists/researchers to carry out future investigations on further novel designs and valued property-performance attributes.
This study conducted a systematic literature review on current and emerging trends in the use of artificial intelligence (AI) for community surveillance, using the PRISMA methodology and the paifal.ai tool for the selection and analysis of relevant sources. Five main thematic areas were identified: AI technologies, specific applications, societal impact, regulations and public policy. Our findings revealed exponential growth in the development and implementation of AI technologies, with applications ranging from public safety to environmental monitoring. However, this advancement poses significant challenges related to privacy, ethics and governance, driving a debate on the need for appropriate regulations. The analysis also highlighted the disparity in the adoption of these technologies among different communities, suggesting a need for inclusive policies to ensure equitable benefits. This study contributes to the understanding of the current scenario of AI in community policing, providing a solid foundation for future research and developments in the field.
Rapid population growth and inadequate adherence to scientific and managerial principles in urban planning have intensified numerous challenges, pushing major Iranian cities toward instability. Tehran, as the capital and one of the most urbanized regions in the country, faces significant sustainability threats that require immediate attention. These challenges are not unique to Tehran but represent a broader issue faced by rapidly urbanizing cities worldwide, particularly in developing countries. Addressing such challenges is critical to fostering sustainable development on a global scale. While urban sustainability has been extensively studied, limited research has focused on the indicators of urban instability and their tangible impacts on sustainable urban planning. This study aims to bridge this gap by identifying and analyzing key factors contributing to urban instability across economic, environmental, and social dimensions, with Tehran serving as a representative case. The findings reveal that economic instability is driven by uncertainty in economic policies, fluctuating housing prices, non-standard housing conditions, income disparity, unemployment, and cost of living pressures. Environmental instability is exacerbated by climate change, urban heat islands, floods, transportation mismanagement, energy insecurity, pollution, and insufficient green infrastructure. Social instability arises from limited social interaction, unequal access to services, weak community participation, social harms, and diminished urban safety and welfare. By framing these local challenges within a global context, the study underscores the interconnectedness of these dimensions and highlights the necessity for integrated, evidence-based approaches that combine local insights with global best practices. The findings aim to contribute to the broader discourse on sustainable urban development by offering actionable insights and strategies that can be adapted and implemented in other rapidly urbanizing cities. This research serves as a guide for policymakers, urban planners, and stakeholders worldwide, emphasizing the importance of holistic and resilient urban strategies to address the multifaceted challenges of sustainability and instability.
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