The Urabá region, known for its banana production, faces significant challenges due to seasonal droughts that affect crop productivity. The implementation of innovative technologies, such as efficient irrigation systems, is presented as a potential solution to improve the sustainability and profitability of plantations. This study validates the implementation of an irrigation system in a banana (Musa spp.) plantation located in the region of Urabá, in order to meet the water needs of the crop during periods of drought. A case study was carried out in a banana plantation in the region of Urabá, considering the maximum and minimum monthly losses due to drought, and a random sample was used to measure the weight before and after the implementation of the irrigation system, in order to carry out an economic analysis. The study shows that the implementation of a sprinkler irrigation system increases the average weight of the harvested bunches by 20%, which is reflected in an annual increase of 30.3% of exported boxes, obtaining satisfactory results in terms of internal rate of return, cost-benefit ratio and return on investment. The implementation of irrigation systems makes it possible to increase competitiveness in international markets, especially in regions such as Urabá, where the use of these technologies is still incipient.

Since its inception in 2013, “The Belt and Road Initiative” has become an important engine driving global economic growth. The initiative has not only promoted infrastructure construction in countries along the Belt and Road but also strengthened financial integration, unimpeded trade, people-to-people exchanges, and policy communication. In this context, higher education, as an important avenue for talent training and scientific and technological innovation, is of great significance to promoting the economic and social development of countries along the Belt and Road. By strengthening academic cooperation with Chinese universities, Kyrgyzstan can enhance its curriculum, adopt advanced teaching methods, and integrate cutting-edge research to foster more skilled labor. In addition, innovation and technology transfer through higher education partnerships can drive sustainable economic growth and diversification. This paper explores the strategic path of integrating higher education into the Belt and Road. Initiative, focusing on academic collaboration, enhancing R&D capabilities, and fostering an entrepreneurial ecosystem.

“Global South” is undoubtedly a broad term that typically refers to developing countries with varying degrees of economic, cultural and political influence. The rise of the Global South signifies the importance of reassessing the existing international order. In terms of international relations theory, this should be an innovative, progressive and reflective field of study. However, this research is predominantly led by the Western mainstream international relations theories. This often neglects the internal and external factors in the development processes of other countries, the formation of relationship frameworks, foreign policy formulation, and the need of foreign relations. Despite the ongoing and intense debate over the innovation of international relations theory, it is difficult to see it keeping pace with contemporary developments. Various schools and thoughts frequently innovate only within their foundational frameworks. Therefore, for Global South countries, there is the need for international relations theories that can reflect their specific needs and actual conditions. This does not only require breaking away from the westcentric theoretical framework, but ensuring that the innovation process is aligned with practical realities that recognize mutual interests and encompass both local and global perspectives. This approach should involve a comprehensive reflection on international relations, allowing innovation of international relations theories to genuinely “enter” the Global South countries.

Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myoinositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistancerelated protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (p < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (p > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (p < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FUresponsive ones at 5-FU concentrations greater than 2.5 μg/mL (p < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.

Disinformation can be defined as false information deliberately initiated to cause harm to a person, social group, organization, or country. Gendered disinformation then attacks or undermines people based on gender or weaponizes gendered narratives for political, social, or economic objectives. Gendered disinformation comes in different forms, such as harmful social media posts and graphics, sexual fabrications, and other forms of conspiracy theories. It is used in various situations and at different places. This research discussed the instances of gendered disinformation and harmful online narratives that are recognizable and visible. It sheds light on the potential direct and indirect impact on youth experiences. In this study, the young participants (aged 18–30) focused on the instances of the existing online narratives of gendered discrimination from Belgium, Greece, Latvia, Spain, and Türkiye. The research provided an initial analysis of what “gendered information and harmful online narratives” look like and some recommendations from youth perspectives on countering the issues. The study concluded that there is a need for more research, further harmonization of legal frameworks, and strengthened capacity to detect gendered disinformation, propaganda, and hate speech.