Freeze-thawing plays a vital role in enhancing materials in medicines. Here, we describe the F-T process of synthesis of Poly (vinyl alcol)- Methylene blue single strand- Mxene (PVA–MB-ssDNA –Mxene), which may be effective for gen delivery applications. The PVA –MB-ssDNA –Mxene hydrogel was formed using 1,3,5 consecutive cycles. We also demonstrated that PVA –MB-ssDNA –Mxene hydrogel can be formed by the affection of DNA with PVA and the MXene network. The F-T process shows the new intra molecular bond of PVA-PVA, compared to the non F-T hydrogel which formed by a biologic crosslinking as MB-ssDNA. Scanning electron microscopy reported that the microstructure. The differential scan shows three endothermic peaks at 70, 180, and 300 ℃ for water loss and decomposition. The swelling behavior rapidly increased due to the PVA chains in the F-T methods and then became stable. With a high concentration of MB-DNA, the tensile strength was slightly high, and the swelling behavior was low. Our results indicated that the PVA –MB-ssDNA –Mxene hydrogel using F-T process would have more suitable structural features as gene hydrogel carrier which need greater mechanical strength and stability in body analyses.
Based on the resource-based view and institutional theory, this study investigates the impact of their environmental management capabilities and environmental, social, and governance (ESG) pressure on the non-financial performance of small and medium-sized enterprises (SMEs). In particular, it examines the interaction effect of ESG pressures on the relationship between SMEs’ environmental management capabilities and non-financial performance. For this study, a total of 1865 SME lists were obtained through Jeonnam Techno Park and Jeonnam Small Business Job and Economy Promotion Agency. Based on this, a total of 127 questionnaires were returned as a result of a telephone, e-mail, and online survey, and finally, an empirical analysis was conducted based on 120 questionnaires. We conducted an empirical analysis of Korean SMEs and obtained the following results: First, environmental management capabilities have a significant, positive effect on SMEs’ non-financial performance. Second, ESG pressure has a significant, negative effect on the non-financial performance of SMEs. Next, we analyzed the moderating effect of ESG pressures and observed that ESG pressures strengthen the positive effect of environmental management capabilities on non-financial performance. Based on the resource-based perspective and institutional theory, this study provides meaningful academic implications by examining environmental management capabilities and ESG pressures, which have not been identified in previous studies, as factors of non-financial performance that are becoming important under the new management paradigm, such as climate change and ESG. Furthermore, while ESG pressure has a significant negative effect on non-financial performance, we find that it is a moderating variable that strengthens the relationship between SMEs’ environmental management capabilities and non-financial performance, which has useful academic and practical implications for ESG and strategic management.
This paper contributes to the understanding of how flexibility in the number of members in a decision-making committee in a multistage project can enhance the accuracy and efficiency of the decisions taken. While most projects typically employ a fixed number of decision makers, the paper demonstrates the advantages of adjusting the committee size according to the project’s varying complexity at different phases of the project. In particular, we show that allowing for flexibility in the size of a committee increases the likelihood of reaching a correct decision under the unanimity rule. We analyze this issue when the decision maker’s competence is independent of the state of nature and when it is not. The results are compared to those under the simple majority rule.
This paper investigates the impact of financial inclusion on financial stability in BRICS countries from 2004 to 2020. Using a panel smooth transition regression model, the results reveal a U-shaped relationship between financial inclusion and financial stability. Financial inclusion reduces financial stability up to a threshold of 44.7%. Beyond this point, financial inclusion contributes to greater financial stability, through gradual transitions. Enhanced financial inclusion supports banks in stabilizing their deposit funding by facilitating access to more stable, long-term funds and alleviating the negative impacts of fluctuations in returns. Furthermore, the study examines the role of institutional quality in shaping the financial inclusion-financial stability nexus, indicating a significant positive effect, especially in the upper regime. These findings provide valuable insights for financial regulatory authorities, highlighting the importance of promoting financial inclusion in BRICS economies and adapting regulations to mitigate potential risks to global financial stability.
Incest is one of the most serious forms of sexual abuse that occurs between a father and his daughter. It involves a parent committing something forbidden to their own child, which violates moral standards. This incestuous relationship has a significant impact on the survivors’ psychology, body, and emotions, affecting all aspects of their lives. This study explores the long-term effects experienced by individuals in Malaysia who have survived father-daughter incest (FDI). This study conducted in-depth interviews with 11 key persons from several agencies involved in handling FDI cases in Malaysia. The findings reveal that those who experienced FDI frequently suffered long-term issues. It is important for everyone involved in assisting these individuals. This is aligned with the global Sustainable Development Goals (SDGs), particularly Goal 3, which emphasises the value of good health and well-being for all. It also aligns with Malaysia’s MADANI concept, which emphasises protecting and promoting everyone’s human rights. FDI survivors can receive the protection and assistance they require to live healthier and more successful lives by implementing an effective strategy that includes mental health support, powerful laws, and community education.
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