The objective of this research was to evaluate the unit rates of MSW generation in Cumba in the years 2016 and 2022. The calculations were based on the weights of the MSW disposed in the dump located 5 km from the city of Cumba since 2012. The GPC, physical composition, density, humidity were determined in the years 2016 and 2022, studied according to the methodology and group classification of Peruvian regulations. The results show that 5.45 Tn/day⁻¹ are generated in 2016, 4.37 Tn/day⁻¹ in 2022; according to its physical composition, 82% RO, 14% MICVC and 4% MISVC in 2016; 77% RO, 16% MICVC, 7% MISVC in 2022; density 137.90 kg/m⁻³ in 2016 and 172.69 kg/m⁻³ in 2022; humidity 67.67% in 2016 and 63.43% in 2022. It was also found that in 100.00% there is no solid waste treatment; Everything generated in homes, businesses and streets is evacuated to the final disposal site, which is a dump. In 2022, Cumba acquired 10 hectares to have adequate sanitary infrastructure and begin the closure and recovery of its current dump. This study will contribute to providing accurate data on MSW generation that allows the local government to promote the optimization of collection routes and schedules, resulting in cost savings and reduction of carbon emissions in the Amazon Region. Therefore, it is necessary to raise awareness at all levels of society through various means of communication and education, so that the risks of spreading health risks can be minimized by improving MSW management.

The CO₂  heat pump air conditioning system of new energy vehicle is designed, and the vehicle model of CO₂  heat pump module and heat management system is established based on KULI simulation. The effects of refrigerant charge, running time and compressor speed on the heat pump air conditioning system is studied, and the energy consumption is compared with the PTC heating system and the CO₂ heat pump air conditioning system without waste heat recovery. The results show that the optimal charge for full-service operation is 750 g; increasing the compressor speed can increase the cooling capacity, so that the refrigerant temperature in the passenger compartment and battery inlet can quickly reach the appropriate temperature, but the COP_h, COP_c are reduced by 2.5% and 1.8% respectively. By comparing it with PTC heating and CO₂ heat pump air conditioning systems without waste heat recovery, it is found that the energy consumption of this system is only for the PTC heating systems 42.5%, without waste heat recovery carbon dioxide heat pump air conditioning system of 86.6%. It greatly saves energy, but also increased the waste heat recovery function, so that the system supply air temperature increased by 26%, improve passenger cabin comfort. This  provides a reference for the future experimental research of CO₂ heat pump air conditioning and heat management system. 

Diabetic retinopathy (DR) is a major cause of blindness globally. Effective screening programs are essential to mitigate this burden. This review outlines key principles and practices in implementing DR screening programs, emphasizing the roles of technology, patient education, and healthcare system integration. Our analysis highlights key principles for establishing successful screening initiatives, including the importance of regular screenings, optimal intervals, recommended technologies, and necessary infrastructure. We emphasize the roles of healthcare providers, patients, and policymakers in ensuring the effectiveness of these programs. Our recommendations aim to support the creation of robust policies that mitigate the impact of DR, ultimately improving public health outcomes and reducing the incidence of blindness due to diabetic retinopathy.

This research aimed to investigate the role of humanizing leadership in enhancing the effectiveness of change management strategies within organizations. Specifically, it focused on how humanizing leadership influences change outcomes and the extent to which organizational culture moderates this relationship. The study addressed critical questions regarding the impact of leadership behaviors, such as model vulnerability, emotional intelligence, open communication, and psychological safety on effective change management and employee performance. A quantitative approach was employed to provide a comprehensive analysis of the phenomena. Quantitative data were collected from a sample of 325 employees through surveys that measured perceptions of Humanizing leadership behaviors, organizational culture, and change outcomes. Data was analyzed by IBM SPSS 26.0. The findings revealed that humanizing leadership behaviors significantly enhances the success of change initiatives, primarily through improved employee engagement and reduced resistance. Organizational culture was found to play a moderating role, amplifying the positive effects of empathetic and inclusive leadership practices. The study provides actionable recommendations for organizational leaders and managers to foster a culture that supports humanizing leadership. By adopting leadership strategies that emphasize vulnerability, empathy, and inclusivity, organizations can enhance their adaptability and resilience against the backdrop of continuous change. These findings are particularly valuable for enhancing managerial practices and informing policy within corporate settings.