Objective: Standardizing image acquisition protocols and image quality across cameras is an important need in imaging, in particular in multi-center clinical trials and the use of image analysis and machine learning algorithms. The objective of this study was to examine the effect of ordered subset expectation maximization (OSEM) reconstruction parameters on the quantitative image quality of cardiac perfusion SPECT images in different typical SPECT cameras and therefore assess the need to change the parameter values across cameras. Methods: The analysis was carried out by comparing the defect contrast-to-noise ratio (CNR) at 12 OSEM subset-iteration combinations. Eight frames were reconstructed using the SIMIND Monte Carlo Simulation package. An activity of 370 MBq (10mCi) and projection acquisition interval of 20 seconds per projection were used. Attenuation (AC) and scatter corrections (SC) were performed in this study for all images. Results: The 16-2 subset-iteration combination yielded the highest CNR and defect contrast values for both cameras. The difference between CNR values for two cameras was found to be close to 5%. Conclusions: Monte Carlo simulations can be useful to investigate how quantitative image quality behaves with respect to reconstruction parameters and correction algorithms in a controlled environment. In this study, the use of different camera brands did not seem to significantly affect the lesion detectability. Further simulations with more extended range of parameters and camera brands may be conducted in the future to quantify further the variability between different brands of cameras.

Rural sub-Saharan Africa faces limited medical access, healthcare worker shortages, and inadequate health information systems. Mobile health (mHealth) technologies offer potential solutions but remain underdeveloped in these settings. This review aims to explore the sociocultural context of mHealth adoption in rural sub-Saharan Africa to support sustainable implementation. A comprehensive Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) search was conducted in databases like PubMed, MEDLINE, and African Journals Online, covering peer-reviewed literature from 2010 to 2024. Qualitative studies of mHealth interventions were included, with quality assessed via the Critical Appraisal Skills Program (CASP) checklist and data synthesized using a meta-ethnographic approach. Out of 892 studies, 38 met the inclusion criteria. Key findings include sociocultural factors like community trust influencing technology acceptance, local implementation strategies, user empowerment in health decisions, and innovative solutions for infrastructure issues. Challenges include privacy concerns, increased healthcare worker workload, and intervention sustainability. While mHealth can reduce healthcare barriers, success depends on sociocultural alignment and adaptability. Future interventions should prioritize community co-design, privacy protection, and sustainable, infrastructure-aware models.