The development of flexible, wearable electronic devices is one of the future directions of technology development. Flexible conductive materials are important supporting materials for wearable electronic devices. Polymer has excellent flexibility; it is an important way to prepare flexible conductors from polymer-based conductive composites. In this paper, the research progress of polymer-based flexible conductive composites is summarized in terms of preparation and characterization methods. The key factors to realize flexible conductors are put forward, namely, the maintenance of excellent polymer elasticity and the realization of stability. The design and preparation of the extensible conductor with high-elasticity matrix and nanofiller are introduced in detail, and the problems in the current research are summarized.

Benzoxazine resin, a new type of phenolic resin, has many advantages, such as a strong molecular design, no small molecular release in the curing process, excellent thermal stability and mechanical properties, and a high residual carbon ratio. Thus, it is important for electronic communication industry matrix material. To meet the needs of high-frequency and high-speed communication technology for low-dielectric polymer resin, the low-dielectric modification of benzoxazine resin is of great significance to the high frequency and high-speed propagation of the signal, which attracts a wide range of materials researchers’ attention. In this paper, we review a series of studies on the low dielectric modification of benzoxazine resin in recent years, including the synthesis of new monomers, inorganic - organic hybridization, copolymerization with other resins, and low molecular weight benzoxazine resin research trends.

Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

The ways of developing functional textiles based on nanomaterials were introduced, and the latest research achievements of nanomaterials in such aspects as flame retardancy, antibacterial, super-hydrophobic, self-cleaning, UV resistance, and anti-static textiles were reviewed. The main technical obstacles to the large-scale application of nanomaterials in functional textiles were pointed out, the possible solutions were discussed, and the development of functional textiles by nanomaterials has been prospected.