Through Qualitative Comparative Analysis (QCA) on destination attractiveness characteristics at the country level, this study identifies attribute configurations in the pre- and post-pandemic period to analyze the changes and differences generated by an exogenous event (COVID-19). The results suggest that the destination attractiveness attributes work together, in multidimensional configurations, to increase leisure travel volume. We found an important change in pat-terns/configurations of attractiveness between the pre- and post-pandemic scenarios. Our findings suggest that the destination attributes may change in importance and valuation or disappear for some configurations. The conclusion has implications for the stakeholders related to the destination attractiveness development, showing possible patterns of tourism attributes to guide the action to improve the resilience in the tourism sector and recover these activities in a disaster scenario.

Improving the practical skills of Science, Technology, Engineering and Mathematics (STEM) students at a historically black college and university (HBCU) was done by implementing a transformative teaching model. The model was implemented on undergraduate students of different educational levels in the Electrical Engineering (EE) Department at HBCU. The model was also extended to carefully chosen high and middle schools. These middle and high school students serve as a pipeline to the university, with a particular emphasis on fostering growth within the EE Department. The model aligns well with the core mission of the EE Department, aiming to enhance the theoretical knowledge and practical skills of students, ensuring that they are qualified to work in industry or to pursue graduate studies. The implemented model prepares students for outstanding STEM careers. It also increases enrolment, student retention, and the number of underrepresented minority graduates in a technology-based workforce.

In this paper advanced Sentiment Analysis techniques were applied to evaluate public opinions reported by rail users with respect to four major European railway companies, i.e., Trenitalia and Italo in Italy, SNCF in France and Renfe in Spain. Two powerful language models were used, RoBERTa and BERT, to analyze big amount of text data collected from a social platform dedicated to customers reviews, i.e., TrustPilot. Data concerning the four European railway companies were first collected and classified into subcategories related to different aspects of the railway sector, such as train punctuality, quality of on-board services, safety, etc. Then, the RoBERTa and BERT models were developed to understand context and nuances of natural language. This study provides a useful support for railways companies to promote strategies for improving their service.

Objective: To describe magnetic resonance imaging (MRI) findings of the brain in patients younger than 65 years who were studied by transcranial Doppler (TCD) with microbubble contrast, with a history of cryptogenic cerebrovascular accident (CVA) and suspected patent foramen ovale (PFO).

Materials and methods: This retrospective cross-sectional study included patients of both sexes, younger than 65 years of age.

Results: Our sample (n = 47.47% male and 53% female, mean age is 42 years) presented high-intensity transient signals (HITS) positive in 61.7% and HITS-negative in 38.3%. In HITS-positive patients, lesions at the level of the subcortical U-brains, single or multiple with bilaterally symmetrical distribution, predominated. In patients with moderate HITS, lesions in the vascular territory of the posterior circulation predominated.

Conclusion: In patients younger than 65 years with cryptogenic stroke and subcortical, single or multiple U-shaped lesions with bilateral and symmetrical distribution, a PFO should be considered as a possible cause of these lesions.

Four alloys based on niobium and containing about 33wt.%Cr, 0.4wt.C and, in atomic content equivalent to the carbon one, Ta, Ti, Hf or Zr, were elaborated by classical foundry under inert atmosphere. Their as-cast microstructures were characterized by X-ray diffraction, electron microscopy, energy dispersion spectrometry and while their room temperature hardness was specified by Vickers indentation. The microstructures are in the four cases composed of a dendritic Nb-based solid solution and of an interdendritic NbCr₂ Laves phase. Despite the MC-former behavior of Ta, Ti, Hf and Zr usually observed in nickel or cobalt-based alloys, none of the four alloys contain MC carbides. Carbon is essentially visible as graphite flakes. These alloys are brittle at room temperature and hard to machine. Indentation shows that the Vickers hardness is very high, close to 1000HV_10kg. Indentation lead to crack propagation through the niobium phase and the Laves areas. Obviously no niobium-based alloys microstructurally similar to high performance MC-strengthened nickel-based and cobalt-based can be expected. However the high temperature mechanical and chemical properties of these alloys remain to be investigated.

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.