Over 90% of cancer-related mortality worldwide is due to metastatic disease since the dynamic tumor microenvironment poses huge challenges in preventing the spread of metastatic cancer. Introducing the advent of advance biomaterials and their swift evolution, this review highlights the great potential of innovative biomaterials to proficiently tackle the metastatic tumor environment. Focusing on four distinct categories of biomaterials systems, action mechanism of biomaterials utilized in anti-tumor therapy is explained in detail: 1. Nanoplatforms sensitive to biochemical cues including pH, redox, and enzymes are known as stimuli-responsive nanoplatforms that react according their environment, 2. Smart nanoplatforms changing their morphology to penetrate impermeable physical barriers at tumor site, 3. Ingenious biomaterial participating in tumor normalization, and 4. Nanoplatforms with real-time theranostic capabilities due to innate feedback-loop mechanism. Ingeniously structured biomaterials with extensive evidence in preclinical efficacy encourage their inclusion in metastatic tumor therapy however, their utilization in medical settings is prevented due to various challenges; impractical manufacturing cost, regulatory and safety issues as well as large-scale production are major challenges restraining their widespread use. A concrete framework is proposed in this review to accelerate the biomaterial structure standardization process, following the GMP and other regulatory guidelines with the aim of implementing biomaterial-based tumor diagnostics and therapies. Since incorporating advancing technologies in tumor therapy such AI-driven, autonomous biomaterial structure or patient-specific tumor models would enable confront the proliferating metastatic tumor cases.

This study investigates the willingness of Indonesian consumers, particularly in West Java, to pay for green products by applying and expanding the Theory of Planned Behavior (TPB). It examines how perceived green product value and willingness to pay premiums influence consumer intentions and behavior toward green purchases. The research highlights the gap between consumers’ willingness to pay for environmentally friendly products and the actual sales of such products. By incorporating perceived value and willingness to pay into the TPB framework, the study aims to find what factors that can address the gap particularly in a developing country context to contribute to shaping a pro-environmental socio-cultural community in Indonesia and mitigates country’s significant environmental challenges. In the context of 251 young consumers in Indonesia, this study finds that subjective norms do not significantly influence purchase intentions. However, attitudes and behavioral controls do effectively encourage green behavior, suggesting that societal norms for green behavior may not be fully established. In addition, while willingness to pay a premium and perceived value of green purchases can influence green behavior, consumers are generally reluctant to pay higher prices for environmentally friendly products.

This study investigates the impacts of converting agricultural land into agrotourism areas on environmental, socio-cultural, and economic perspectives within Batukliang District, Central Lombok Regency, Indonesia. With a case study approach, this qualitative descriptive research employed interviews with three target groups: local farmers, residents, and tourism actors. The findings revealed seven key points identified as influences affecting the socio-cultural aspects of land change, including community impact, cultural preservation, cultural identity loss, community dynamics change, local cultural commercialization, cultural heritage loss, and traditional livelihoods. The results also unveiled nine financial impacts, 8 of which were associated with economic implications such as economic challenges, risk management, brand building, costs and investments, market access, increased revenue, and income diversity, which contribute positively to local economic development. The study concluded that integrating community involvement empowerment strategies, income diversification, sustainable farming promotion, and land-use regulation is crucial for developing a successful sustainable agrotourism destination.

More and more scholars are paying attention to the economic and environmental responsibilities undertaken by firms. Firm sustainability has become a hot topic in current research. This article aims to analyze the impact of various dimensions of digital green technology innovation on firm sustainability. The “digital green technology innovation” in this research is a new variable explored based on previous research, and the five dimensions of the variable are created based on the POLE theory. This research uses authoritative Chinese databases to collect data on various dimensions of digital green technology innovation and sustainable development of companies, and uses a fixed effects model for regression analysis. The results indicate that the implementation of various dimensions of digital green technology innovation will promote the firm sustainability. Moreover, in firms with strong profitability, this performance is significantly better than in those with weak profitability.

Enhancing the emphasis on incorporating sustainable practices reinforces a linear transition towards a circular economy by organizations. Nevertheless, although studies on circular economy demonstrate an increasing trend, the drivers that support circular economy practices towards sustainable business performance in the Small and Medium-Sized Enterprise (SME) sector, especially in developing nations, demand exploration. Accordingly, the study examines circular economy drivers, i.e., green human resource management, in establishing sustainability performance and environmental dynamism as moderating variables. The study engaged 207 SMEs and 621 respondents who were analyzed utilizing structural equation modeling. The analysis indicated that sustainable business performance was affected by green human resource management and a circular economy. Subsequently, the circular economy mediated the linkage between green human resources management and sustainable business performance. The environmental dynamism moderated the linkage between green human resources management and the circular economy.