Introduction: the presence of anti-CCP is an important prognostic tool for rheumatoid arthritis (RA), but its relationship with the activity of the disease and functional capacity is still being investigated. Objectives: to study the relationship between anti-CCP and the indices of disease activity, functional capacity and structural damage, by means of conventional radiography (CR) and magnetic resonance imaging (MRI), in stabilized RA. Methods: cross-sectional study of RA patients with one to 10 years of disease. The participants were subjected to clinical evaluation with anti-CCP screening. Disease activity was assessed by means of the Clinical Disease Activity Index (CDAI) and functional capacity by means of the Health Assessment Questionnaire (HAQ). CR was analyzed by the Sharp van der Heijde index (SmvH) and MRI by the Rheumatoid Arthritis Magnetic Resonance Image Scoring System (RAMRIS). Results: 56 patients were evaluated, with median (IIq) of 55 (47.5–60.0) years, 50 (89.3%) were female among whom 37 (66.1%) were positive for anti-CCP. The median (IIq) of CDAI, HAQ, SmvH and RAMRIS were 14.75 (5.42–24.97), 1.06 (0.28–1.75), 2 (0–8) and 15 (7–35), respectively. There was no association between anti-CCP and CDAI, HAQ, SmvH and RAMRIS. Conclusion: our results did not establish the association of anti-CCP with the severity of the disease. So far, we cannot corroborate the anti-CCP as a prognostic tool in RA established.
This paper provides a comparative perspective on infrastructure provision in developing Asia's three largest countries: China, India, and Indonesia. It discusses their achievements and shortfalls in providing network infrastructure (energy, transport, water, and telecommunications) over the past two decades. It documents how three quite distinct development paths—and very different levels of national saving and investment—were manifested in different trajectories of infrastructure provision. The paper then describes the institutional, economic, and policy factors that enabled or hindered progress in providing infrastructure. Here, contrasting levels of centralization of planning played a key role, as did countries’ differing abilities to mobilize infrastructure-related revenue streams such as user charges and land value capture. The paper then assesses future challenges for the three countries in providing infrastructure in a more integrated and sustainable way, and links these challenges with the global development agenda to which the three countries have committed. The concluding recommendations hope to provide a platform for further policy and research dialogue.
The whole world is in a fuel crisis nearly approaching exhaustion, with climate change knocking at our doorsteps. In the fight against global warming, one of the principle components that demands technocratic attention is Transportation, not just as a significant contributor to atmospheric emissions but from a much broader perspective of environmental sustainability.
From the traditional technocratic aspect of transport planning, our epiphany comes in the form of Land Use integrated sustainable transport policy in which Singapore has been a pioneer, and has led the way for both developed and developing nations in terms of mobility management. We intend to investigate Singapore’s Transport policy timeline delving into the past, present and future, with a case by case analysis for varying dimensions in the present scenario through selective benchmarking against contemporary cities like Hong Kong, London and New York. The discussions will include themes of modal split, land use policy, vehicular ownership, emission policy, parking policy, safety and road traffic management to name a few. A visualization of Singapore’s future in transportation particularly from the perspective of automated vehicles in conjunction with last mile solutions is also detailed.
This paper describes the significance, content, progress and corresponding basic theory and experimental research methods of micron/nanometer scale thermal science and engineering, which is one of the latest cutting-edge disciplines, and analyzes the effects of micron nanometer devices on the scale effect series of challenging hot issues, discussed the corresponding emergence of some new phenomena and new concepts, pointed out that the micron/nano thermal science aspects of the recent development of several types of theory and experimental technology success and shortcomings, and summed up a number for the exploration of the new ways and new directions, especially on some typical micron/nano-thermal devices and micro-scale biological heat transfer in some important scientific issues and their engineering applications were introduced.
Chinese municipalities have developed a large stock of capital assets during a period of rapid growth and urbanization, but have yet to modernize asset management practices. Cities face challenges such as premature decline of fixed assets and spiking liabilities related to operating and maintaining assets. This paper evaluates the asset management practices in three selected small cities and towns in China, using a benchmarking assessment tool followed by an in-depth field assessment. The paper finds that overall performance is below half the international benchmark for good practice in all three cities. Management practices are considerably more advanced for land than for buildings and infrastructure. Key deficiencies in data availability and reporting, governance, capacity, and financial management indicate increased risks for local government finance and the delivery of public services. For small cities and towns where public revenues are often uncertain and limited, urban public services will be at risk of deterioration unless good asset management practices are put in place. The paper recommends strategic actions for upper and lower levels of government, to advance local asset management practices and facilitate the reform agenda.
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