Researchers from all over the world have been working tirelessly to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic since the World Health Organization (WHO) proclaimed it to be a pandemic in 2019. Expanding testing capacities, creating efficient medications, and creating safe and efficient COVID-19 (SARS CoV-2) vaccinations that provide the human body with long-lasting protection are a few tactics that need to be investigated. In clinical studies, drug delivery techniques, including nanoparticles, have been used since the early 1990s. Since then, as technology has advanced and the need for improved medication delivery has increased, the field of nanomedicine has recently seen significant development. PNPs, or polymeric nanoparticles, are solid particles or particulate dispersions that range in size from 10 to 1000 nm, and their ability to efficiently deliver therapeutics to specific targets makes them ideal drug carriers. This review article discusses the many polymeric nanoparticle (PNP) platforms developed to counteract the recent COVID-19 pandemic-related severe acute respiratory syndrome coronavirus (SARS-CoV-2). The primary subjects of this article are the size, shape, cytotoxicity, and release mechanism of each nanoparticle. The two kinds of preparation methods in the synthesis of polymeric nanoparticles have been discussed: the first group uses premade polymers, while the other group depends on the direct polymerization of monomers. A few of the PNPs that have been utilized to combat previous viral outbreaks against SARS-CoV-2 are also covered.
Healthcare mobile applications satisfy different aims by frequently exploiting the built-in features found in smart devices. The accessibility of cloud computing upgrades the extra room, whereby substances can be stored on external servers and obtained directly from mobile devices. In this study, we use cloud computing in the mobile healthcare model to reduce the waste of time in crisis healthcare once an accident occurs and the patient operates the application. Then, the mobile application determines the patient’s location and allows him to book the closest medical center or expert in some crisis cases. Once the patient makes a reservation, he will request help from the medical center. This process includes pre-registering a patient online at a medical center to save time on patient registration. The E-Health model allows patients to review their data and the experiences of each specialist or medical center, book appointments, and seek medical advice.
Renewable energy is gaining momentum in developing countries as an alternative to non-renewable sources, with rooftop solar power systems emerging as a noteworthy option. These systems have been implemented across various provinces and cities in Vietnam, accompanied by government policies aimed at fostering their adoption. This study, conducted in Ho Chi Minh City, Vietnam investigates the factors influencing the utilization of rooftop solar power systems by 309 individuals. The research findings, analyzed through the Partial least squares structural equation modeling (PLS-SEM) model, reveal that policies encouragement and support, strategic investment costs, product knowledge and experience, perceived benefits assessment, and environmental attitudes collectively serve as predictors for the decision to use rooftop solar power systems. Furthermore, the study delves into mediating and moderating effects between variables within the model. This research not only addresses a knowledge gap but also furnishes policymakers with evidence to chart new directions for encouraging the widespread adoption of solar power systems.
Introduction, purpose of the study: In Central Europe, in Hungary, the state guarantees access to health care and basic health services partly through the Semmelweis Plan adopted in 2011. The Health Plan aims to optimize and transform the health system. The objectives of hospital integration, as set out in the Plan, started with the state ownership of municipal hospitals in 2012, continued with the launch of integration processes in 2012–2013 and culminated today. The transformation of a health system can have an impact on health services and thus on meeting the needs of the population. We aim to study the effectiveness of integration through access to CT diagnostic testing. Our hypothesis is that integration has resulted in increased access to modern diagnostic services. The specialty under study is computed tomography (CT) diagnostic care. Our research shows that the number of people receiving CT diagnostic care has increased significantly because of integration, which has also brought a number of positive benefits, such as reduced health inequalities, reduced travel time, costs and waiting lists. Test material and method: Our quantitative retrospective research was carried out in the hospital of Kalocsa through document analysis. The research material was comparing two time periods in the Kalocsa site of Bács-Kiskun County, Southern Hungary. The number of patients attending CT examinations by area of duty of care according to postal codes was collected: Pre-integration period 2014.01.01–2017.11.30. (Kalocsa did not have CT equipment, so patients who appeared in Kecskemét Hospital but were under the care of Kalocsa), post-integration period 2017.12.01–2019.12.31. (period after the installation of CT in Kalocsa). The target group of the study consisted of women and men together, aged 0–99 years, who appeared for a CT diagnostic examination. The study sample size was 6721 persons. Linear regression statistics were used to evaluate the results. Based on empirical experience, a SWOT analysis was carried out to further investigate the effectiveness of integration. Results: As a result of the integration, the CT scan machine purchased in the Kalocsa District Hospital has enabled an average of 129.7 patients per month to receive CT scans on site without travelling. The model used is significant, explaining 86% of the change in the number of patients served (F = 43.535; p < 0.001, adjusted R2 = 0.860). The variable of integration in the model is significant, with an average increase in the number of patients served of 129.7 per month (t = 22.686; p < 0.001) following the introduction of CT due to integration. None of the month variables representing seasonal effects were found to be significant, with no seasonal effect on care. The SWOT analysis has clearly identified the strengths, weaknesses, opportunities and threats related to the integration, the main outcome of which is the acquisition of a CT diagnostic tool. Conclusions: Although we only looked at one segment of the evidence for the effectiveness of hospital integration, integration in the study area has had a positive impact on CT availability, reducing disparities in care.
This paper analyses the impact of an integrated business management system on business operations in trade in Republic of Croatia. The integration of management systems provides various benefits to a company, so the aim of this paper is to analyse the impacts of integrated management systems on the business operations of trade companies in the Republic of Croatia. The purpose of this paper is to examine and analyse, but also to adequately theoretically argue the impact of transformational leadership, quality culture, and the degree of integration on the development of integrated management systems. Empirical research investigated integrated management systems in companies in the trade sector in the Republic of Croatia. Based on the set conceptual model and research results, we conclude that companies with a highly developed quality culture have proven management system integration. Our research didn’t confirm the significance of transformational leadership in interpreting changes in the degree of management system integration, but it highlights the positive correlation between the application of quality culture and integration; confirms the substantial impact of integrated management systems on both internal and external benefits, emphasizing its strategic imperative for sustained business success.
The main long-term goal of international communities is to achieve sustainable development. This issue is currently highly topical in most European Union (EU) countries due to the ongoing energy crisis. Building Integrated Photovoltaics (BIPV), which can be integrated into the building surface (roof or facade), thereby replacing conventional building materials, contributes significantly to achieving zero net energy buildings. However, fire safety is important when using BIPV as a structural system in buildings, and it is essential that the application of BIPV as building facades and roofs does not adversely affect the safety of the buildings, their occupants, or the responding firefighters. As multifunctional products, BIPV modules must meet fire safety requirements in the field of electrical engineering as well as in the construction industry. In terms of building regulations, the fire safety requirements of the BIPV must comply with national building regulations. Within this article, aspects and fire hazards associated with BIPV system installations will be defined, including proposals for installation and material requirements that can help meet fire safety.
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