Objective: This study investigates the efficacy and safety of epidural infiltration with drugs and an oxygen-ozone mixture for treating cervicobrachialgia due to disc-radicular conflict or on a degenerative basis, utilizing both retrospective analysis and direct visualization techniques. Methods: A retrospective study involving 10 patients treated with epidural infiltrations of an oxygen-ozone mixture and cortisone was conducted. The procedures were performed under CT guidance to ensure precise delivery and to monitor the diffusion of the injected substances. Pain levels were assessed using the Numerical Rating Scale (NRS) and treatment efficacy was evaluated based on symptom relief and reduction in NSAID intake. Results: Significant pain reduction was observed post-treatment, with median NRS scores decreasing from 9 (baseline) to 2 (follow-up), and a significant decrease in on-demand NSAID intake. Only one minor complication of a headache was reported. The study also demonstrated the ability of ozone to diffuse through the epidural adipose tissue, potentially enhancing treatment efficacy. Conclusion: The combined use of an oxygen-ozone mixture and cortisone for epidural infiltration is an effective and safe treatment for cervicobrachialgia, offering significant pain relief and minimizing the risk associated with traditional epidural injections. This technique presents a viable non-surgical option for patients suffering from disc-radicular conflict or degenerative conditions.

The COVID-19 pandemic in 2019 heralded a downturn in the Thai economy, particularly in the tourism and hospitality sectors which rely heavily on international tourists. To decrease the dependence of international tourists, this research outlined three objectives as 1) explore and classify the high-end domestic tourism market among 77 provinces in Thailand, 2) study the potential and readiness of tourism resources and tourism products to cater to the demand of high-end domestic tourists, and 3) suggest tourism management approaches for domestic high-end tourists after the crisis. Both quantitative and qualitative research methodologies were applied to achieve the research objectives. Income was used to identify and segment high-end domestic tourists living in 77 provinces in Thailand, while a verified questionnaire collected data from 1200 respondents nationwide. Forty-one experts from different tourism-related agencies at local and regional levels were targeted using purposive sampling techniques, and semi-structured interviews were conducted to acquire qualitative data. High-end domestic tourists, classified by monthly income, were segmented into Silver (50,000–70,000 THB), Gold (70,001–90,000 THB), Diamond (91,001–110,000 THB), and Platinum groups (Over 110,001 THB). These high-end domestic tourists shared both similarities and differences in tourism needs, preferences, and behaviors. Sixteen provinces in six domestic regions demonstrated the potential and readiness of tourism resources and products to satisfy the needs, preferences, and behaviors of high-end domestic tourists.