There are numerous studies reported on the usage of the sapindus emarginatus (SE) fruit in cancer and other treatments in the past few years. In this study, crude SE fruit extract was prepared and it was further used to synthesis gold nanoparticles (Au Nps). The synthesized Au Nps were left embedded in the SE fruit extract. The Au Nps embedded in the SE fruit extract (SE-Au Nps) were characterized using UV-Visiable Spectroscopy, Centrifugal Particle Size analyzer (CPS), Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). MTT assay was carried out for both SE fruit extract and SE-Au Nps on MCF7 breast cancer cell line and thus compared. The UV-Visible Absorbance for the SE-Au Nps was obtained at 543 nm. The centrifugal particle size analysis of the Au Nps embedded in SE fruit extract showed the size of the nanoparticles to be widely varying with higher fraction of particles between the size ranges of 15 to 20 nm. The morphology of the Au Nps embedded in SE fruit extract was observed using SEM. The presence of Au Nps in SE fruit extract was confirmed using FTIR. The results of the MTT assay on MCF7 breast cancer cell line proved that the % cell viability was less for SE-Au Nps than that of the SE fruit extract alone. Thus, the antiproliferative activity of the SE fruit extract was significantly enhanced by embedding it with Au Nps and it can be effectively used in therapeutic applications after further studies.

Our intention in assembling this special issue of the Journal of Infrastructure, Policy and Development is to offer a state-of-the-art tour through the political economy issues associated with the provision of public infrastructure, and with the use of Public-Private Partnerships (PPPs) in particular. Anyone who is familiar with PPPs cannot fail to be impressed by the diversity of positions and claims regarding their properties. Some scholars maintain that PPPs are an efficient tool to enhance productivity due to their ability to manage demand-side risk. In contrast, other scholars see in PPPs a scheme whereby the public assumes the risk while the private partner takes the profit.

The provision of infrastructure and related services in developing Asia via public–private partnership (PPP) increased rapidly during the late 1990s. Theoretical arguments support the potential economic benefits of PPPs, but empirical evidence is thin. This paper develops a framework identifying channels through which economic gains can be derived from PPP arrangement. The framework helps derive an empirically tractable specification that examines how PPPs affect the aggregate economy. Empirical results suggest that increasing the ratio of PPP investment to GDP improves access to and quality of infrastructure services, and economic growth will potentially be higher. But this optimism is conditional, especially on the region’s efforts to further upgrade its technical and institutional capacity to handle complex PPP contracts.

Antioxidants are derivatives of vitamin C or beta-carotene that prevent reactions stimulated by oxygen, peroxides, or free radicals, thus reducing the oxidative stress. They have found their way into many uses in treating several human diseases and reducing the risk of developing diseases like cancer. In view of this property, the present study was focussed in identifying several plants possessing antioxidative properties and which were also conserved in the ex-situ park of CSIR – Central Institute of Mining and Fuel Research, Dhanbad, India. Fifteen medicinal plants including herbs, shrubs and grasses are reported in this paper, and a collective insight has been presented about their antioxidant properties and the present state of their pharmacological applications. The specific chemical constituents abundant in the leaves, roots, stems, seeds and fruits of each of these plants have also been dealt with. To report a few antioxidant pharmacological preparations from Ayurvedic literature are Vimang, Maharishi Amrit Kalash (MAK4, MAK5), Maharishi Ayurved (MA631, MA47), MA Raja’s Cup, MA Student Rasayana and MA Ladies Rasayana. This review has been attempted to enhance the importance of the plants which are generally being neglected, so that it can used by the local people in rural areas for their cultivation and it will also pave the pathway for their subsequent future use in medicinal and research industry for drug formulation.

Many questions of control theory are well studied for systems which satisfy to the relative degree definition. If this definition is fulfilled then there exists linear state-space transform reducing system to a very convenient canonical form where zero dynamics is a part of system’s equations. Algorithms of such reduction are well-known. However, there exist systems which don’t satisfy this definition. Such systems are the subject of investigation in the presented paper. To investigate their properties here we suggest to consider an analogue of the classical relative degree definition – the so-called column-wise relative degree. It turned out that this definition is satisfied in some cases when classical relative degree doesn’t exist. We introduce this notion here, investigate it properties and suggest algorithm for reducing systems to the column-wise relative degree compliant form if possible. It is possible to show that systems with column-wise relative degree also can be reduced to a convenient canonical form by a linear state-space transformation. Some problems arise from the fact that some systems which do not have relative degree can be reduced to a form with it using linear inputs or outputs transform. Here we show that this is an interesting mathematical problem, which can be solved with the help of properties of relative degree, formulated and proved in this paper.

Synthesis of macro-mesoporous Titania (Titanium dioxide-TiO₂) nanospheres was successfully achieved using a modified template-free methodology to incorporate macroporous channels into a mesoporous TiO₂ framework to form mixed macro-mesoporous TiO₂ spheres (MMPT), which were doped with carbon dots (C-dots) to form improved nanocomposites (C-dots@MMPT). Elemental composition, surface bonding and optical properties of these nanocomposites were characterized by X-ray diffraction (XRD), Fourier transforms infrared spectroscopy (FTIR) and ultraviolet-visible absorption spectroscopy (UV-VIS). Evaluation of photocatalytic activity for each (C-Dots@MMPT) sample was performed via degrading the Methylene Blue (MB) dye compared with bare samples (MMPT) under visible light irradiation using 300 Watt halogen lamp.