Fungi can be used to remove or degrade polluting compounds through a mycoremediation process. Sometimes even more efficiently than prokaryotes, they can therefore be used to combat pollution from non-biodegradable polymers. Cellulose acetate is a commonly used material in the manufacture of cigarette butts, so when discarded, it generates pollution. The fungus Pleurotus ostreatus has the ability to degrade cellulose acetate through the enzymes it secretes. The enzyme hydrolyzes the acetyl group of cellulose acetate, while cellulolytic enzymes degrade the cellulose backbone into sugars, polysaccharides, or cellobiose. In addition to cellulose acetate, this fungus is capable of degrading other conventionally non-biodegradable polymers, so it has the potential to be used to reduce pollution. Large-scale cultivation of the fungus has proven to be more economically viable than conventional methods for treating non-biodegradable polymers, which is an additional advantage.
Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myo-inositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistance-related protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (P < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (P > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (P < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FU-responsive ones at 5-FU concentrations greater than 2.5 μg/mL (P < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.
Renewable energy is gaining momentum in developing countries as an alternative to non-renewable sources, with rooftop solar power systems emerging as a noteworthy option. These systems have been implemented across various provinces and cities in Vietnam, accompanied by government policies aimed at fostering their adoption. This study, conducted in Ho Chi Minh City, Vietnam investigates the factors influencing the utilization of rooftop solar power systems by 309 individuals. The research findings, analyzed through the Partial least squares structural equation modeling (PLS-SEM) model, reveal that policies encouragement and support, strategic investment costs, product knowledge and experience, perceived benefits assessment, and environmental attitudes collectively serve as predictors for the decision to use rooftop solar power systems. Furthermore, the study delves into mediating and moderating effects between variables within the model. This research not only addresses a knowledge gap but also furnishes policymakers with evidence to chart new directions for encouraging the widespread adoption of solar power systems.
Fiscal decentralization is one of the policy implementations of regional autonomy, which authorizes local governments to manage their local finances independently. However, with the evolution of the times and the dynamics that are taking place, the application of fiscal decentralization worldwide is changing at each time of year. Therefore, it is necessary to investigate fiscal decentralization research temporarily over the course of four decades. The study aims to explain the development of research on fiscal decentralization over a period of four decades. This research integrates Scopus database to offer a thorough conceptual and structural overview of the field by integrating bibliometric approaches and content analysis. The research procedure begins with the determination of the scope of the research, the inclusion and exclusion criteria for the selection process, the collection of data on Publish or Perish (PoP), and the execution of bibliometric analysis on VosViewer. The research shows that the type of journal with the highest productivity has sub-topics of economy, public service, development, and environmental. The development of fiscal decentralization research has a positive upward trend and most of the top-ranked journals indicate that fiscal decentralization has links and influences with other variables. It is apparent that the most often keywords emerged and studied in the research on fiscal decentralization are related to efficiency, measure, role, degree, growth, and fiscal federalism. Meanwhile, the least frequent keywords are related to poverty and inequality, health outcome, environmental pollution, Latin America, South Africa, fiscal autonomy, corruption, OECD country, determinant, and public sector. These keywords are the future lines of research that may be used for future research on the topic of fiscal decentralization.
Recent technological advances in the fields of biomaterials and tissue engineering have spurred interest in biopolymers for various biomedical applications. The advantage of biopolymers is their favorable characteristics for these applications, among which proteins are of particular importance. Proteins are explored widely for 3D bioprinting and tissue engineering applications, wound healing, drug delivery systems, implants, etc., and the proteins mainly available include collagen, gelatin, albumin, zein, etc. Zein is a plant protein abundantly present in corn endosperm, and it is about 80% of total corn protein. It is a highly renewable source, and zein has been reported to be applicable in different industrial applications. Lately, it has gained attention in biomedical applications. This research interest in zein is on account of its biocompatibility, non-toxicity, and certain unique physico-chemical properties. Zein comes under the GRAS category and is considered safe for biomedical applications. The hydrophobic nature of this protein gives it an added advantage and has wider applications in drug delivery. This review focuses on details about zein protein, its properties, and potential applications in biomedical sectors.
Bamboo is one of the noble plant species in Ethiopia. Household (HH) income and construction role of highland bamboo (Oldeania alpina (K. Schum.) Stapleto) stands were assessed at Masha district, Southern Ethiopia. Three peasant associations (PAs), Yepo, Yina and Gada, 7–15 key informants and 68, 46, 31 households, respectively were interviewed about the cost and income of bamboo to compare with woody climbers, honey, and mushroom in 2021. Bamboo was one of the main sources of income in all PAs, at least for fencing or house construction. In Yepo, Yina and Gada bamboo accounts 0.7%, 28.1%, 16.3% of the HH NTFP income, respectively. The local people responded that bamboo constructed houses and fences were durable for 15–30 and 2–10 years, respectively. In constructing a 2.44–4.27 m radius local house in Yepo, Yina and Gada 2.4–6 m3, 4.1–5.82 m3 and 3.1–4.3 m3 bamboo culms were harvested at 15, 20, and 30 years interval, respectively by each HH. Bamboo young shoots were also seasonally used for food. Although bamboo provides multiple uses, like substitute for wood and environmental services, it was facing different problems of deforestation. Therefore, policy attention is highly important for bamboo sustainable utilization.
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