Four alloys based on niobium and containing about 33wt.%Cr, 0.4wt.C and, in atomic content equivalent to the carbon one, Ta, Ti, Hf or Zr, were elaborated by classical foundry under inert atmosphere. Their as-cast microstructures were characterized by X-ray diffraction, electron microscopy, energy dispersion spectrometry and while their room temperature hardness was specified by Vickers indentation. The microstructures are in the four cases composed of a dendritic Nb-based solid solution and of an interdendritic NbCr₂ Laves phase. Despite the MC-former behavior of Ta, Ti, Hf and Zr usually observed in nickel or cobalt-based alloys, none of the four alloys contain MC carbides. Carbon is essentially visible as graphite flakes. These alloys are brittle at room temperature and hard to machine. Indentation shows that the Vickers hardness is very high, close to 1000HV_10kg. Indentation lead to crack propagation through the niobium phase and the Laves areas. Obviously no niobium-based alloys microstructurally similar to high performance MC-strengthened nickel-based and cobalt-based can be expected. However the high temperature mechanical and chemical properties of these alloys remain to be investigated.

Nanoparticle V₂O₅ is prepared by the measurement of X-ray diffraction (XRD) and atomic force microscopy (AFM) analyses. The crystallite size = 19.59 nm, optical energy gap = 2.6 eV, an average particle size of 29.58 nm and, RMS roughness of ~6.8 nm. Also, Fourier transformer infrared spectrophotometer (FTIR) showed a porous free morphology with homogeneity and uniformity on the sample surface. The film surface exhibited no apparent cracking and, the grains exhibited large nicely separated conical columnar growth combined grains throughout the surface with coalescence of some columnar grains at a few places. The fabrication of a thin film of V₂O₅ NPs/PSi heterojunction photodetector was characterized and investigated.

The growth of mobile Internet has facilitated access to information by minimizing geographical barriers. For this reason, this paper forecasts the number of users, incomes, and traffic for operators with the most significant penetration in the mobile internet market in Colombia to analyze their market growth. For the forecast, the convolutional neural network (CNN) technique is used, combined with the recurrent neural network (RNN), long short-term memory network (LSTM), and gated recurrent unit (GRU) techniques. The CNN training data corresponds to the last twelve years. The results currently show a high concentration in the market since a company has a large part of the market; however, the forecasts show a decrease in its users and revenues and the growth of part of the competition. It is also concluded that the technique with the most precision in the forecasts is CNN-GRU.

Japan’s investment in the domestic construction industry has fallen to less than half its peak in 1992. Given the country’s declining population, Japanese construction companies must go global to remain profitable. To what extent the Japanese government and Japanese companies can contribute to meeting the growing infrastructure needs in the region is unclear as Japanese companies have long been operating primarily in Japan. The Japanese government has in recent years passed a series of new laws that encourage private sector participation in financing, building and operating public infrastructure. Through involvement in such public projects, Japanese companies have developed the skills and technologies to build a variety of infrastructures that are resilient to natural disasters and adaptable to various geographical conditions and social and economic development. But the major challenge for Japanese companies is to transform their business model drastically from one that relies on the domestic market to one that contributes to the social and economic development of third countries.

Objective: To evaluate the radiographic characteristics of dentigerous cysts (DC) diagnosed at the School of Stomatology of the Universidad Peruana Cayetano Heredia (UPCH) during the period of 2010–2017. Material and methods: Retrospective, descriptive, observational and cross-sectional study, where the panoramic radiographs of 37 cases of DC were selected. Results: The total number of diagnosed cases of dentigerous cysts was 233, which after inclusion and exclusion criteria, 37 cases were obtained, of which 45.9% of cysts were found in the second decade of life with a higher frequency of 51.4 percent for women, and a jaw predilection of 59.5% in all cases. In addition, it was found that 97.3% of the cases were radiolucent, defined limits were found in 67.6%, corticalized edges in 54.1% and unilocular in 94.6%. All dentigerous cysts were associated with a tooth, of which closed apex (48.6%) and tooth displacement (59.5%) were observed. The adjacent tooth was not affected in 56.8% of cases, but its hard lamina was affected (59.5%). The 68.2% of cases did not affect the basal mandibular cortex, but did displace the inferior dental canal (54.5%) and 46.7% of cases displaced the floor of the maxillary sinus. Conclusions: Most of the results obtained on the characteristics in the Peruvian population support previous studies reported in America, Europe and Asia. Radiographically the dentigerous cyst showed characteristics that support its clearly benign behavior.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.