Subcutaneous (SC) drug delivery is one of the best routes of drug administration to patients over intravenous (IV) administration due to the ease of application and patient acceptance. The main limitation of using the SC route is administering larger volumes of drug, greater than 3–5 mL for therapeutic dosages. Wearable injectors on body devices are an attractive option for larger-volume drug delivery to patients. Thus, the need for a self-administration strategy at home is growing faster and is required for the next level of time-dependent and high-volume drug delivery. The advances in low-cost, connected on-body delivery systems hold great opportunity for novel ways of delivering home-based drug therapy in the future.

This work presents the evaluation of iron oxide nanoparticles obtained from the aqueous extract of Eucalyptus grandis. Twenty-three experiments were carried out where the synthesis of nanoparticles was performed by using the aqueous extract together with salts of iron (II) chloride tetrahydrate and iron (III) chloride hexahydrate. A characterization was carried out by IR, TEM and BET, where bands were presented at 3,440.77, 1,559.26 and 445.31 cm⁻¹, indicating the presence of iron oxide nanoparticles. A relatively high monodispersity was evidenced with particles around 9 nm. By means of BET analysis it was found to present a surface area of 131.897 m²/g. Obtaining nanoparticles by this green method presents yield values of 98%, with application in nanotechnology, biomedicine, environmental treatment, among others, making them highly versatile and their production cost is relatively low.

We investigate the impact on intertemporal distribution caused by a change of policy from tax to deficit financing of public investment, using a simple theoretical framework which combines the one-period McGuire-Olson economy with the conventional long-run Solow economy. This theoretical framework provides a simple way to highlight some significant interdependencies between private and public investments as well as the negative impact of taxation on aggregate productivity, and to trace some possible transmission mechanisms between deficit financing policies and the long-run path of consumption per head. The main tentative (theoretical) result is that although under fairly acceptable assumptions the likely impact of a deficit financing policy is to benefit the present at the expense of the future, under equally acceptable assumptions concerning the possibility of an excessive macro private saving–investment propensity, and/or of a significant productivity loss due to the excess burden of taxation, the adverse intertemporal distributional impact of deficit financing might become negligible, or even disappear altogether.

This study investigates how financial cognitive abilities influence individual investors’ intentions to engage in the stock market, particularly considering the mediating role of financial capability. It seeks to address the gaps in understanding the factors that drive investors’ participation in emerging markets like Pakistan, highlighting the importance of financial knowledge, financial planning, and financial satisfaction and financial capability. Data were collected from 377 individual investors through a self-administered questionnaire using a cross-sectional design and non-probability convenience sampling approach. Results reveal that financial knowledge affects investors’ intentions both directly and indirectly, with financial capability serving as a partial mediator. Financial planning influences intentions indirectly through complete mediation, while financial satisfaction affects intentions in both direct and indirect ways, with partial mediation. The study provides valuable insights for the researchers, individual investors, governmental officials, policymakers, and stock market regulators in context of emerging economies like Pakistan, highlighting key determinants of stock market participation.

In this regard the key factor determining the success of the mining industry is the cost of electricity. By understanding the risks associated with crypto mining industry. The method is based on systemic literature review and bibliometric analysis exploring keyword “bitcoin mining”. This review paper studies 50 papers for the period of 2019–2023. The results propose recommendations for crypto miners. Currently, the results confirm that bitcoin mainly depends on the consumption of inexpensive electricity. Consequently, the bitcoin network predominantly uses energy in regions where it is abundant and cannot be stored or exported. Most miners rely on electricity generated from hydroelectric power plants, geysers and geothermal sources, which are not easy to transport or store. Bitcoin will continue to look for such cost-effective and underutilized energy sources, as mining in urban areas or industrial centers will remain financially unviable. If the price of bitcoin stabilizes and a sufficient number of miners enter the market, it is quite possible that in the near future we may witness a fivefold increase in their energy consumption.

Considering the application of the polymer electrolyte membrane fuel cell (PEMFC), the separator thickness plays a significant role in determining the weight, volume, and costs of the PEMFC. In addition, thermal management, i.e., temperature distribution is also important for the PEMFC system to obtain higher performance. However, there were few reports investigating the relation between the temperature profile and the power generation characteristics e.g., the current density distribution of PEMFC operated at higher temperatures (HT-PEMFC). This paper aims to study the impact of separator thickness on the temperature profile and the current density profile of HT-PEMFC. The impact of separator thickness on the gases i.e., H₂, O₂ profile of HT-PEMFC numerically was also studied using CFD software COMSOL Multiphysics in the paper. In the study, the operating temperature and the relative humidity (RH) of the supply gas were varied with the separator thickness of 2.0 mm, 1.5 mm, and 1.0 mm, respectively. The study revealed that the optimum thickness was 2.0 mm to realize higher power generation of HT-PEMFC. The heat capacity of the separator thickness of 2.0 mm was the biggest among the separators investigated in this study, resulting in the dry-up of PEM and catalyst layer was lower compared to the thinner separator thickness. It also clarified the effects of separator thickness of profile gases, e.g., O₂, H₂O, and current density profile became larger under the higher temperature and the lower RH conditions.