The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.

The development of entrepreneurship in fisheries operations is an important component of eliminating poverty. Fisherman obviously produce fishery goods, despite the broad recognition of the positive role that entrepreneurship can play in the reduction of poverty. Integration into one’s society and economy are increasingly beginning to be seen as an essential component of entrepreneurial success. This study aims to investigate the cultural and entrepreneurial attitudes of fishermen involved in the production of fishery products in the Province of West Sumatra, Indonesia, accordingly with a particular focus on marine resource conservation areas in village development. In this development, the descriptive design of capitals was utilized. This design included interviews, a questionnaire survey, and a review of the relevant body of literature. As a result, the purpose of the study was to propose an alternative model for the development of villages that would be considered novel in Indonesia. The findings demonstrated that the model makes a contribution to enhancing the socio-economic, cultural, and social capabilities of a group of fishermen. In conclusion, tourism that is focused on social entrepreneurship has the potential to boost entrepreneurial attitudes as well as the atmosphere surrounding community understanding of creative village development. We came to the conclusion that implementing tourism with a focus on social entrepreneurship could increase entrepreneurial attitudes and create an atmosphere that is more conscious of the needs of the community in village development.

Climate change has affected the coasts of the world due to numerous factors, including the change in the intensity and frequencies of the storms and the increase in the mean sea level, among others. Argentina has extensive coastal areas, and research and monitoring tasks are expensive and require a significant number of personnel to cover large geographical areas. Given this, citizen science has become a tool to increase scientific research's spatial and temporal extension. Therefore, the paper aims to analyze the methodology and development of the citizen science project in Villa Gesell and its lessons for applying them in future coastal environmental monitoring projects. The methodology was based on an experience of the project co-created between activists and researchers. This project included four phases for social and physical aspects: training for the citizens, theoretic and practical aspects of coastal dynamics, and how to measure its geomorphological and oceanographic variations; data collection: the activists who received the training performed the measurements to monitor the beach; data analysis by scientists; and dissemination of results; the report data were disseminated by citizens in their community. The analysis of case studies in citizen science projects generates a fundamental learning arena to apply in future projects. Among the positive aspects were the phases established for their development and the methodology used to collect beach monitoring data.

The enormous biological potential of herbal products is one of the main reasons for their frequent use in the production of dietary supplements and functional foods, which, in addition to their nutritional properties, have pharmacological and physiological effects. New scientific knowledge on the isolation of pharmacologically active compounds from complex matrices has led to significant advances in this field. Today, the process of extraction plays a significant scientific role, with “green” technologies occupying a special place in today’s science. Herbal medicine is one of the oldest human skills, which has worn off with its centuries-old application in the path of modern medicine. Microwave-assisted extraction, or more simply, microwave extraction, is a new extraction technique that combines traditional extraction solvents and microwaves. The mentioned method takes less time, consumes less energy, and has strong penetration power into the plant matrix to obtain more oils, but it can also reduce production costs. This can eventually increase the quality of the final product and reduce the product price at the consumer level. Microwave-assisted extraction could be useful to the herbal industry for oil extraction as well as other pharmaceutically important plant components. Based on a comparison and study of published literature, this research examines the present state of extraction procedures. This review includes a detailed discussion of the most important extraction techniques.