Objective: This study investigates the efficacy and safety of epidural infiltration with drugs and an oxygen-ozone mixture for treating cervicobrachialgia due to disc-radicular conflict or on a degenerative basis, utilizing both retrospective analysis and direct visualization techniques. Methods: A retrospective study involving 10 patients treated with epidural infiltrations of an oxygen-ozone mixture and cortisone was conducted. The procedures were performed under CT guidance to ensure precise delivery and to monitor the diffusion of the injected substances. Pain levels were assessed using the Numerical Rating Scale (NRS) and treatment efficacy was evaluated based on symptom relief and reduction in NSAID intake. Results: Significant pain reduction was observed post-treatment, with median NRS scores decreasing from 9 (baseline) to 2 (follow-up), and a significant decrease in on-demand NSAID intake. Only one minor complication of a headache was reported. The study also demonstrated the ability of ozone to diffuse through the epidural adipose tissue, potentially enhancing treatment efficacy. Conclusion: The combined use of an oxygen-ozone mixture and cortisone for epidural infiltration is an effective and safe treatment for cervicobrachialgia, offering significant pain relief and minimizing the risk associated with traditional epidural injections. This technique presents a viable non-surgical option for patients suffering from disc-radicular conflict or degenerative conditions.

Research on community resilience has been ongoing for decades. Several studies have been carried out on resilience in different groups and contexts. However, few address the relationship between community resilience and depopulated rural areas. This study aims to dig deeper into this, considering the concrete impact of population decline in Spain. We carried out a systematic review of the most relevant contributions. A search protocol was developed and used to consult ten databases. Different combinations of terms such as ‘community resilience’, ‘rural’, and ‘depopulation’, or related terms, were used. 22 scientific texts were analysed. We obtained a set of publications that demonstrate the heterogeneity of research methods, approaches and analytical processes applied to the study of this relationship. A mostly qualitative approach was observed, either as the main technique or complementary to documentary reviews. The results underscore the complex nature of rural depopulation and related constructs. It emphasizes the specific importance of community resilience in these territories in terms of social capital, endogenous resources, sustainability, economic dynamism, local responsibility and effective governance. The findings identify a scarce mention to social intervention professions, which should have a more important role due to their core values. In the studies reviewed, it appears as an emerging and scientifically relevant area to explore, both for investigation and intervention purposes. The strength of a multidisciplinary approach to addressing the phenomena appears in the discussion as a main potential line of research.

Fruits are a source of vitamins. Mango is one of the abundantly nutritional fruits. Vitamin B9, or folic acid, is one of the important vital amines due to its role in preventing neural deficiency. Several beneficial micro-organisms are used for the synthesis of folic acid. In this study, Lactobacillus acidophilus, Leuconostoc mesenteroides, Streptococcus thermophilus, and Saccharomyces cerevisiae were used. Saccharomyces cerevisiae synthesized folic acid as compared to other organisms. There were five different concentrations of mango pulp that were analyzed for folic acid synthesis (5%, 10%, 15%, 20%, and 30%). The initial concentration of pulp was 133.37 mg kg⁻¹, but after fermentation with four micro-organisms it got reduced. As compared to the other three organisms, Saccharomyces cerevisiae synthesizes 17.15 mg kg⁻¹, 30.14 mg kg⁻¹, 28.62 mg kg⁻¹, 21.70 mg kg⁻¹, and 21.78 mg kg⁻¹, respectively, at different pulp concentrations of 5%, 10%, 15, 20%, and 30%. Vitamin C increased to 320 mg as compared to the control, and there was no significant difference between the four micro-organisms. Antioxidants also showed positive results at different concentrations of pulp. There was an increase in titratable acidity and a decrease in pH recorded for the 24 h fermentation period. In this variety, the color of mango pulp slightly changes to yellow shades due to the breakdown of pigments, so this effects the *b value in between the pulp concentrations. Data supports the enrichment of folic acid, which will further support the utilization of beneficial micro-organisms in food beverages. 

In recent years, incidents of school bullying have been on the rise, attracting increasing attention from society. School bullying refers to the repeated and sustained use of force or coercion by individual or group of students to oppress other students in terms of power or status, resulting in many physical and psychological problems for the victims. This paper introduces the definition, classification, role types, and the impact on victims, as well as interventions for school bullying. Studies have shown that school bullying can have negative psychological consequences for victims, such as anxiety and depression, making timely intervention extremely important. Intervention measures include educating the active perpetrators, victims, and bystanders. In particular, the "STAC" course is an effective way to educate bystanders. In summary, school bullying is a problem that requires timely intervention, and it requires joint efforts from schools, families, and society to solve.

This study informs the academic and policy debate on the policy effectiveness of exchange rate interventions on exchange rate levels and volatility. Using a constructed data set comprising daily data on exchange rates, monetary policy fundamentals, exchange rate intervention dates and magnitudes of those interventions as well as financial news speculation of such interventions, we empirically estimate the policy effectiveness of Bank of Japan interventions in the exchange rate over the 12-year period between 2010 and 2022. This allows us to investigate the policy effectiveness of a variety of exchange rate interventions, or news of exchange rate interventions, across different time-horizons. We find that policy interventions in the yen exchange rate are more effective over short-horizons than long-horizons, more effective when the policy objective is a competitive devaluation of the yen rather than a revaluation, and more effective at influencing the level of the yen against major world currencies other than the US dollar. In fact, for the yen-dollar rate, we find that policy interventions may have the unintended consequences of weakening the yen (when the policy intention is to strengthen it) and increasing volatility in the yen-dollar exchange rate.