Nanomaterials are a recently discovered type of material that is gaining importance and receiving a lot of attention from researchers. Due to their numerous advantages, scholars are studying nanoparticles extensively. The articles in this issue that discuss the various applications of nanoparticles are very interesting. The majority of these articles focus on the use of nanoparticles in the medical sector and their contributions to environmental protection.

The problem of the synthesis of new type nanomaterials in the form of nano-coatings with sub-nanometric heterogeneity has been formulated. It has been presented an analysis of influences of physical vapor deposition in ultrahigh vacuum on the process of intermixing a film with a substrate, including the results, which has been obtained under the formation of transition metal – silicon interface. The generalization of the obtained experimental results develops an approach to the development of new nano-coatings with low-dimensional heterogeneity. The principles of constructing such low-dimensional nano-coatings, their properties and possible applications are considered.