Objective: Sleep-wake disorders is a common disease in children and adolescents. In recent years, there has been an increasing number of studies on the intervention of exercise therapy in sleep-wake disorders. This study aims to systematically review the development status, research frontiers, research hotspots and development trends of exercise therapy in the through bibliometric methods. Methods: The data comes from the Web of Science Core Collection database. Select all the original data from the establishment of the database to 26 April 2024. Summarize the external characteristics of the literature through Web of Science, Use Excel 2021, Origin 2021, VOS viewers 1.6.20 and Cite Space 6.3.R1 to visually analyze countries/regions, institutions, journals, authors, co-cited references and co-occurrence keywords, use the bibliometric online analysis platform (https://bibliometric.com/) to analyze the changes of keywords and extended keywords over the years. Results: We received a total of 775 publications. The works were sourced from 1429 institutions in 75 countries/regions, published in 113 journals, and written by 4332 authors. The number of publications peaked in 2012, 2018, 2019 and 2021 respectively. In the United States, Harvard University and Children (Basel) have the highest number of publications in this field. The analysis of co-cited references shows that there are three main research frontiers in this field, including 24-hour exercise behavior guidelines for children and adolescents, COVID-19 lockdown and cardiometabolic risk. Screen time, mental health, validity, depression, guidelines, stress, and mediterranean diet are still the current research hotspots in the field, and may become potential research hotspots in the future. Conclusion: The development of research in the field of exercise therapy for children and adolescents with sleep-wake disorders is relatively slow, and there is still a lack of cross-regional scientific research collaborations between countries/regions, institutions and individuals. Our research suggests that it may be a worthwhile research direction to promote the establishment of healthy lifestyle behaviors in the gathering environment of children and adolescents, formulate targeted policies for disease prevention, diagnosis and management, strictly implement preventive measures, improve the level of diagnosis, and dig deep into the precise treatment plan of diseases.

Understanding the factors that influence early science achievement is crucial for developing effective educational policies and ensuring equity within the education system. Despite its importance, research on the patterns of young children achieving science learning milestones and the factors that can reduce disparities between students with and without disabilities remains limited. This study analyzes data from the Early Childhood Longitudinal Study of Kindergarten Cohort 2011 (ECLS-K: 2011), which includes 18,174 children from 1328 schools across the United States, selected through a complex sampling process and spanning kindergarten to 5th grade. Utilizing survival analysis, the study finds that children with disabilities achieve science milestones later than their peers without disabilities, with these disparities persisting from early grades. The research highlights the effectiveness of center-based programs in enhancing science learning, particularly in narrowing the achievement gap between children with and without disabilities. These findings contribute to the broader discourse on equity in the education system and policy by introducing novel methodologies for assessing the frequency and duration of science learning milestones, and by providing insights into effective strategies that support equitable science education.

This review discusses the significant progress made in the development of CNT/GO-based biosensors for disease biomarker detection. It highlights the specific applications of CNT/GO-based biosensors in the detection of various disease biomarkers, including cancer, cardiovascular diseases, infectious diseases, and neurodegenerative disorders. The superior performance of these biosensors, such as their high sensitivity, low detection limits, and real-time monitoring capabilities, makes them highly promising for early disease diagnosis. Moreover, the challenges and future directions in the field of CNT/GO-based biosensors are discussed, focusing on the need for standardization, scalability, and commercialization of these biosensing platforms. In conclusion, CNT/GO-based biosensors have demonstrated immense potential in the field of disease biomarker detection, offering a promising approach towards early diagnosis. Continued research and development in this area hold great promise for advancing personalized medicine and improving patient outcomes.