This review discusses the significant progress made in the development of CNT/GO-based biosensors for disease biomarker detection. It highlights the specific applications of CNT/GO-based biosensors in the detection of various disease biomarkers, including cancer, cardiovascular diseases, infectious diseases, and neurodegenerative disorders. The superior performance of these biosensors, such as their high sensitivity, low detection limits, and real-time monitoring capabilities, makes them highly promising for early disease diagnosis. Moreover, the challenges and future directions in the field of CNT/GO-based biosensors are discussed, focusing on the need for standardization, scalability, and commercialization of these biosensing platforms. In conclusion, CNT/GO-based biosensors have demonstrated immense potential in the field of disease biomarker detection, offering a promising approach towards early diagnosis. Continued research and development in this area hold great promise for advancing personalized medicine and improving patient outcomes.
Cysteine is one of the body’s essential amino acids to build proteins. For the early diagnosis of a number of diseases and biological issues, L-cysteine (L-Cys) is essential. Our study presents an electrochemical sensor that detects L-cysteine by immobilizing the horseradish peroxidase (HRP) enzyme on a reduced graphene oxide (GCE) modified glassy carbon electrode. The morphologies and chemical compositions of synthesized materials were examined using Fourier transform infrared spectroscopy (FTIR) and field-emission scanning electron microscopy (FESEM). The modified electrode’s electrochemical behavior was investigated using cyclic voltammetry (CV). Cyclic voltammetry demonstrated HRP/rGO/GCE has better electrocatalytic activity than bare GCE in the oxidation of L-cysteine oxidation in a solution of acetate buffer. The electrochemical sensor had a broad linear range of 0 µM to 1 mM, a 0.32 µM detection limit, and a sensitivity of 6.08 μA μM−1 cm−2. The developed sensor was successfully used for the L-cysteine detection in a real blood sample with good results.
Photovoltaic systems have shown significant attention in energy systems due to the recent machine learning approach to addressing photovoltaic technical failures and energy crises. A precise power production analysis is utilized for failure identification and detection. Therefore, detecting faults in photovoltaic systems produces a considerable challenge, as it needs to determine the fault type and location rapidly and economically while ensuring continuous system operation. Thus, applying an effective fault detection system becomes necessary to moderate damages caused by faulty photovoltaic devices and protect the system against possible losses. The contribution of this study is in two folds: firstly, the paper presents several categories of photovoltaic systems faults in literature, including line-to-line, degradation, partial shading effect, open/close circuits and bypass diode faults and explores fault discovery approaches with specific importance on detecting intricate faults earlier unexplored to address this issue; secondly, VOSviewer software is presented to assess and review the utilization of machine learning within the solar photovoltaic system sector. To achieve the aims, 2258 articles retrieved from Scopus, Google Scholar, and ScienceDirect were examined across different machine learning and energy-related keywords from 1990 to the most recent research papers on 14 January 2025. The results emphasise the efficiency of the established methods in attaining fault detection with a high accuracy of over 98%. It is also observed that considering their effortlessness and performance accuracy, artificial neural networks are the most promising technique in finding a central photovoltaic system fault detection. In this regard, an extensive application of machine learning to solar photovoltaic systems could thus clinch a quicker route through sustainable energy production.
Creating a crop type map is a dominant yet complicated model to produce. This study aims to determine the best model to identify the wheat crop in the Haridwar district, Uttarakhand, India, by presenting a novel approach using machine learning techniques for time series data derived from the Sentinel-2 satellite spanned from mid-November to April. The proposed methodology combines the Normalized Difference Vegetation Index (NDVI), satellite bands like red, green, blue, and NIR, feature extraction, and classification algorithms to capture crop growth's temporal dynamics effectively. Three models, Random Forest, Convolutional Neural Networks, and Support Vector Machine, were compared to obtain the start of season (SOS). It is validated and evaluated using the performance metrics. Further, Random Forest stood out as the best model statistically and spatially for phenology parameter extraction with the least RMSE value at 19 days. CNN and Random Forest models were used to classify wheat crops by combining SOS, blue, green, red, NIR bands, and NDVI. Random Forest produces a more accurate wheat map with an accuracy of 69% and 0.5 MeanIoU. It was observed that CNN is not able to distinguish between wheat and other crops. The result revealed that incorporating the Sentinel-2 satellite data bearing a high spatial and temporal resolution with supervised machine-learning models and crop phenology metrics can empower the crop type classification process.
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