This study aims to elucidate the impact of marketing investment dimensions (MTS, MTOE, ROMI) on profitability indicators (ROA, ROE, GPM, OPM) and sustainable growth indicators (SGR, ARG) for service companies. The study population consisted of 135 service companies listed on the Amman Stock Exchange. A purposive sample of 55 companies was selected from this population. Financial reports and statements from 2018–2022 for these companies were analyzed to achieve the study objectives, employing appropriate statistical methods like multiple regression to test hypotheses. Previous literature shows conflicting results regarding the relationship between marketing investment dimensions and profitability/sustainable growth. Some studies found positive impacts, while others did not. This study contributes to this debate by providing statistical evidence. The results show that higher MTS, MTOE, and ROMI have a positive impact on SGR, OPM and ROA but a negative impact on GPM, ARG, and ROE. This underscores that marketing investments should be viewed in conjunction with overall operating expenses. Companies that control other expenses and increase the marketing investment proportion of total operating expenses may achieve better financial performance. Marketing investment metrics can serve as useful diagnostics and measures of effectiveness for improving marketing profitability, financial performance, and growth. In summary, this study statistically demonstrates the nuanced impacts of marketing investments on service company profitability and sustainable growth indicators. The results emphasize analyzing marketing spends in context of broader expenses and overall company financial health.

Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myoinositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistancerelated protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (p < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (p > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (p < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FUresponsive ones at 5-FU concentrations greater than 2.5 μg/mL (p < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.

This study explores the complex dynamics of handling augmented reality (AR) data in higher education in the United Arab Emirates (UAE). Although there is a growing interest in incorporating augmented reality (AR) to improve learning experiences, there are still issues in efficiently managing the data produced by these apps. This study attempts to understand the elements that affect AR data management by examining the relationship between the investigated variables: faculty readiness, technological limits, financial constraint, and student engagement on data management in higher education institutions in the UAE, building on earlier research that has identified these problems. The research analyzes financial constraints, technological infrastructure, and faculty preparation to understand their impact on AR data management. The study collected detailed empirical data on AR data management in UAE higher education environments using a quantitative research methods approach, surveys. The reasons for choosing this research method include cost-effectiveness, flexibility in questionnaire design, anonymity and confidentiality involved in the chosen methods. The results of this study are expected to enhance academic discourse by highlighting the obstacles and remedies to improving the efficiency of AR technology data management at higher education institutions. The findings are expected to enlighten decision-making in higher education institutions on maximizing AR technology’s benefits for improved learning outcomes.

Plant growth-promoting rhizobacteria (PGPR) offer eco-friendly alternatives to chemical fertilizers, promoting sustainable agriculture by enhancing soil fertility, reducing pathogens, and aiding in stress resistance. In agriculture, they play a crucial role in plant growth promotion through the production of agroactive compounds and extracellular enzymes to promote plant health and protection against phytopathogens. In the rhizosphere, diverse microbial interactions, including those with bacteria and fungi, influence plant health by production of antimicrobial compounds. The antagonism displayed by rhizobacteria plays a crucial role in shaping microbial communities and has potential applications in developing a natural and environmentally friendly approach to pest control. The rhizospheric microbes showcase their ecological importance and potential for biotechnological applications in the context of plant-microbe interactions. The extracellular enzymes produced by rhizospheric microbes like amylases, chitinases, glucanases, cellulases, proteases, and ACC deaminase contribute to plant processes and stress response emphasizing their importance in sustainable agriculture. Moreover, this review highlights the new paradigm including artificial intelligence (AI) in sustainable horticulture and agriculture as a harmonious interaction between ecological networks for promoting soil health and microbial diversity that leads to a more robust and self-regulating agricultural system for protecting the environment in the future. Overall, this review emphasizes microbial interactions and the role of rhizospheric microbial extracellular enzymes which is crucial for developing eco-friendly approaches to enhance crop production and soil health.

The current paper aims at spatial presentation in Cinque Terre. The purpose is to reconstruct digital products (maps, statistics, diagrams, and 3D models) and the spatial analysis of the five villages. The goals are the presentation of the geomorphology, geography, population, density, and area. Also, the Strength-Weakness-Opportunities-Threats (SWOT) analysis creates the disadvantages and advantages of the five villages in the region. The methodology is based on the software (G.I.S. Pro, QGIS, Zephyr 3D, Microsoft Excel, Generic Mapping Tool) and the bibliography study. For instance, the construction 3D terrain model shows the buildings, roads, green areas, and land cover of the five villages. The digital products help better “read” the region and emphasize the measurements and location of the region’s elements. The final results contain a message about new technologies and spatial planning. The new technologies have given spatial solutions in the last few years. The innovative, understanding, and attractive cartographical digital products present the geomorphology of the traditional villages in Cinque Terre.

Flood risk analysis is the instrument by which floodplain and stormwater utility managers create strategic adaptation plans to reduce the likelihood of flood damages in their communities, but there is a need to develop a screening tool to analyze watersheds and identify areas that should be targeted and prioritized for mitigation measures. The authors developed a screening tool that combines readily available data on topography, groundwater, surface water, tidal information for coastal communities, soils, land use, and precipitation data. Using the outputs of the screening tool for various design storms, a means to identify and prioritize improvements to be funded with scarce capital funds was developed, which combines the likelihood of flooding from the screening tool with a consequence of flooding assessment based on land use and parcel size. This framework appears to be viable across cities that may be inundated with water due to sea-level rise, rainfall, runoff upstream, and other natural events. The framework was applied to two communities using the 1-day 100-year storm event: one in southeast Broward County with an existing capital plan and one inland community with no capital plan.