Cancer is the 3rd leading cause of death globally, and the countries with low-to-middle income account for most cancer cases. The current diagnostic tools, including imaging, molecular detection, and immune histochemistry (IHC), have intrinsic limitations, such as poor accuracy. However, researchers have been working to improve anti-cancer treatment using different drug delivery systems (DDS) to target tumor cells more precisely. Current advances, however, are enough to meet the growing call for more efficient drug delivery systems, but the adverse effects of these systems are a major problem. Nanorobots are typically controlled devices made up of nanometric component assemblies that can interact with and even diffuse the cellular membrane due to their small size, offering a direct channel to the cellular level. The nanorobots improve treatment efficiency by performing advanced biomedical therapies using minimally invasive operations. Chemotherapy’s harsh side effects and untargeted drug distribution necessitate new cancer treatment trials. The nanorobots are currently designed to recognize 12 different types of cancer cells. Nanorobots are an emerging field of nanotechnology with nanoscale dimensions and are predictable to work at an atomic, molecular, and cellular level. Nanorobots to date are under the line of investigation, but some primary molecular models of these medically programmable machines have been tested. This review on nanorobots presents the various aspects allied, i.e., introduction, history, ideal characteristics, approaches in nanorobots, basis for the development, tool kit recognition and retrieval from the body, and application considering diagnosis and treatment.

During the early spring in the woodlands of eastern North America, Phlox drummondii emerges as a perennial plant adorned with a profusion of blooms in shades of blue, purple, pink, or white. Its evergreen nature adds to its charm. To manage the growth of plants or specific plant parts, plant growth regulators (PGRs) are synthesized and employed, serving as valuable tools for controlling and directing the development of various plant species. A diverse range of ornamental plants, such as Phlox drummondii, have been documented to receive exogenous applications of plant growth regulators (PGRs). Among these regulators, gibberellins (GA) play a vital role by delaying senescence in flowers and promoting the breaking of dormancy in seeds, bulbs, and corms of ornamental plants. The experiment aimed to assess the performance and determine the optimal growth medium for Phlox. Five distinct growth media were employed as treatments during the study, which took place in the Horticulture Department of Gomal University. Collected data underwent analysis through ANOVA and Tuckey HSD tests. The study’s findings revealed that the highest plant height (16 cm) was observed in the control treatment with PGR 1, closely followed by PGR 2 (11.5 cm). The treatment labeled as T5, composed of a mixture of 1/3 sand, 1/3 poultry manure, and 1/3 soil, demonstrated the most favorable results across multiple parameters such as bud initiation (BI), first flower emergence (FFE), flowers per plant (FPP), branches per plant (BPP), leaves per plant (LPP), number of roots (NR), field life of flowers (FLF), and flower diameter (FD). T4, T3, T2, and T1 treatments also exhibited similar positive outcomes, aligning with the promising performance of T5.

The purpose of this study is to investigate customer satisfaction with quality of service known as SERVQUAL improvement or service quality competitiveness in emerging markets. Using Indonesian government medical care as an example the author examines the satisfaction of patients. Information and data were collected through a survey of 399 BPJS users in Indonesia. All data were analyzed using Smart PLS. This study demonstrates that there is a negative value associated with the five-dimensional gap. As a result, the care provided to BPJS patients is below par. Specifically, the sensitivity dimension has the largest disparity at 0.15, while the physical evidence dimension has the smallest at 0.49. In order to raise the level of service provided, it may be necessary to take direct measures or examine tangible evidence. This study develops the relationship between different quality service models. There appears to be a substantial increase in the body of literature in the area of service quality, allowing for constant updates and the incorporation of the lessons learned from the experiences of the departed. These revised guidelines are intended to aid SERVQUAL study participants. The study gives practical support to academics and practitioners in directing service quality improvement through the use of data collected from large-scale surveys of patients and medical professionals as doctors in Indonesia.

To gain a deep understanding of maintenance and repair planning, investigate the weak points of the distribution network, and discover unusual events, it is necessary to trace the shutdowns that occurred in the network. Many incidents happened due to the failure of thermal equipment in schools. On the other hand, the most important task of electricity distribution companies is to provide reliable and stable electricity, which minimal blackouts and standard voltage should accompany. This research uses seasonal time series and artificial neural network approaches to provide models to predict the failure rate of one of the equipment used in two areas covered by the greater Tehran electricity distribution company. These data were extracted weekly from April 2019 to March 2021 from the ENOX incident registration software. For this purpose, after pre-processing the data, the appropriate final model was presented with the help of Minitab and MATLAB software. Also, average air temperature, rainfall, and wind speed were selected as input variables for the neural network. The mean square error has been used to evaluate the proposed models’ error rate. The results show that the time series models performed better than the multi-layer perceptron neural network in predicting the failure rate of the target equipment and can be used to predict future periods.

The performance of five cauliflower cultivars in conventional and alternative phytosanitary management—without the use of synthetic pesticides—was evaluated. Two experiments were conducted at Epagri, Ituporanga Experimental Station in February 2018 and 2019. A randomized block design with four repetitions was adopted, with twenty plants of each cultivar as plots. The seedlings were transplanted on millet and mucuna straw at a spacing of 0.5 m × 0.8 m. We evaluated agronomic yield, inflorescence quality, pest damage and plant diseases, especially bacterial and fungal rots. The cauliflower hybrids Vera, Verona and Serena stood out in productivity and quality, being the most indicated for sowing in off-season crops, in the Alto Vale do Itajaí region. The most productive cultivars were less damaged by bacterial diseases and defoliating caterpillars and without interference of whitefly infestation on yield. The results also reveal that it is possible to control pests and diseases with phytosanitary products of lower toxicity, i.e., with lower residues of synthetic pesticides.

The xanthorrhiza species of the genus Arracacia belongs to the Apiaceae family and is known for its ability to generate tuberous reservoir roots that are harvested annually and marketed fresh in South American countries such as Colombia, Brazil, Venezuela, Peru, Bolivia and Ecuador. In Colombia, arracacha is planted mainly in 15 departments and the regional cultivars are differentiated by the color of the leaves, petiole and tuberous root, the best known being amarilla común or paliverde, yema de huevo, and cartagenera. There are studies that have characterized regional materials by applying a limited number of descriptors, but they do not allow knowing the morphology and phenotypic differentiation of each one; therefore, their definition and characterization constitute a support in breeding programs that allow the efficient use of the genetic potential and increase the knowledge about the diversity of cultivars. Phenotypic characterization and description of three cultivars was performed during two production cycles (2016 and 2018) in two phases (vegetative and productive) applying 74 morphological variables (42 qualitative and 32 quantitative) organized in seven groups of variables: plant, leaf, leaflet, petiole, propagule, stock and tuberous root. A factorial analysis for mixed data (FAMD) was performed, which incorporated a multivariate analysis with all variables and identified 11 discriminant variables, 8 qualitative and 3 quantitative, which can be used in processes of characterization of arracacha materials. A morphological description of each cultivar was made, which means that this is the first complete characterization study of regional arracacha materials in Colombia.