This study evaluates the effectiveness of Indonesia's defense industry policy from 2018 to 2023, focusing on PT Pindad, a pivotal state-owned defense enterprise. Using a Balanced Scorecard (BSC) framework, the study assesses PT Pindad’s performance across financial, customer, internal process, and learning and growth perspectives. The findings reveal strengths in financial stability (Current Ratio at 115.57% in 2023) and customer satisfaction, but challenges in Return on Investment (ROI), which fell from 6% in 2022 to 5.46% in 2023, signaling a need for further internal improvements. A mediation analysis using Shape-Restricted Regression indicates that Research and Development (R&D) serves as a crucial mediator, enhancing the impact of strategic alliances and technology transfer on PT Pindad’s self-reliance, with R&D showing a positive coefficient of β = 0.53 (p < 0.01). The systematic literature review complements these findings, underscoring the role of technology transfer, human capital development, and strategic partnerships as essential components for strengthening PT Pindad’s self-reliance and global competitiveness. Recommendations are made to enhance policy effectiveness by fostering robust technology transfer mechanisms, increasing investment in human capital, and expanding strategic partnerships. This research contributes to the literature on defense industry policies by providing a comprehensive evaluation framework that informs future policy decisions.

There are several factors that generate postharvest losses of Citrus sinensis, but none have been focused on the central jungle of the Junín region of Peru. The objective of this research was to evaluate postharvest losses of Citrus sinensis in the province of Satipo, Junín region of Peru, considering the stages of the production chain. The methodology was applied to descriptive and cross-sectional design. A sample of 10 orange trees, 3 transport intermediaries and 5 traders selected for compliance with minimum volume and quality requirements were used. The °Brix, pH and acidity characteristics of the fruit were determined. Subsequently, absolute and percentage losses were quantified through direct observation, surveys and interviews. The main postharvest losses of Citrus sinensis were 1.50% in harvesting and detaching, 1.75% in transport to the collection center, 2.23% in storage and transport by intermediaries, and 2.90% in storage and sale by retailers. The overall loss was 8.12% throughout the production chain and US$5.75 per MT of C. sinensis harvested. The main damages found were mechanical and biological, caused by poor harvesting and packaging techniques, precarious storage and careless transport of the merchandise.

The MDA-MB-231 cell line is derived from triple-negative breast cancer (TNBC), representing one of the most aggressive forms of breast cancer. Innovative therapeutic strategies, including s targeted therapies using nanocarriers, hold significant promise, particularly for difficult-to-treat cancers such as TNBC. Nanoparticles have transformed the medical field by serving as advanced drug delivery systems for cancer treatment. They play a critical role in overcoming the drug resistance often associated with cancer therapies. When utilized as drug delivery vehicles, nanoparticles can specifically target cancer cells and effectively reduce or eliminate multidrug resistance. Among them, chitosan-coated magnetic nanoparticles (MNPs) have been widely explored for the loading and controlled release of various anticancer agents. In this study, we evaluated the effects of dexamethasone-loaded chitosan-coated MNPs on MDA-MB-231 cell lines. Fourier transform infrared spectroscopy and scanning electron microscopy were employed to verify the successful loading of dexamethasone onto the nanoparticles. To assess cytotoxicity, empty nanoparticles, free drug, and drug-loaded nanoparticles were tested on the cells. The results indicated that empty nanoparticles exhibited no toxic effects. The IC50 value of the free drug was 123 µg/mL, while the IC50 value of the drug-loaded nanoparticles was significantly lower, at 63 µg/mL. These findings confirmed the successful conjugation of dexamethasone to the chitosan-coated MNPs, demonstrating substantial cytotoxic effects on breast cancer cells. Although dexamethasone has been reported to exhibit both tumor-suppressive and pro-metastatic effects, its specific impact on TNBC warrants further investigation in future studies.

This study explores the relationship between GDP growth, unemployment rate, and labor force participation rate in the Gulf Cooperation Council (GCC) countries from 1990 to 2018. Furthermore, the study incorporates control factors such as government spending, trade openness, and energy use into the regression equation. We used panel dynamic ordinary least squares (DOLS) and Fully Modified Ordinary Least Squares (FMOLS) estimators to investigate the relationships between variables in this investigation. The econometric technique accounts for nonstationary, endogeneity bias and cross-sectional dependencies between country-year observations. Cointegration was found among GDP growth, unemployment rate, and labor force participation. Long-term, the unemployment rate has a statistically significant negative effect on economic growth in the GCC nations. Meanwhile, the labor force participation rate significantly influences economic expansion in the long term. The expansion of government expenditures and international trade reduces economic growth. Alternatively, it is discovered that energy consumption has a substantial and positive effect on economic expansion. Okun’s rule and the unidirectional causality from economic growth to unemployment indicate that the primary cause of unemployment in GCC nations is a failure to adequately expand their economies. When developing economic strategies to reduce unemployment, policymakers are particularly interested in determining whether or not economic development and the unemployment rate are cointegrated.

Photovoltaic systems have shown significant attention in energy systems due to the recent machine learning approach to addressing photovoltaic technical failures and energy crises. A precise power production analysis is utilized for failure identification and detection. Therefore, detecting faults in photovoltaic systems produces a considerable challenge, as it needs to determine the fault type and location rapidly and economically while ensuring continuous system operation. Thus, applying an effective fault detection system becomes necessary to moderate damages caused by faulty photovoltaic devices and protect the system against possible losses. The contribution of this study is in two folds: firstly, the paper presents several categories of photovoltaic systems faults in literature, including line-to-line, degradation, partial shading effect, open/close circuits and bypass diode faults and explores fault discovery approaches with specific importance on detecting intricate faults earlier unexplored to address this issue; secondly, VOSviewer software is presented to assess and review the utilization of machine learning within the solar photovoltaic system sector. To achieve the aims, 2258 articles retrieved from Scopus, Google Scholar, and ScienceDirect were examined across different machine learning and energy-related keywords from 1990 to the most recent research papers on 14 January 2025. The results emphasise the efficiency of the established methods in attaining fault detection with a high accuracy of over 98%. It is also observed that considering their effortlessness and performance accuracy, artificial neural networks are the most promising technique in finding a central photovoltaic system fault detection. In this regard, an extensive application of machine learning to solar photovoltaic systems could thus clinch a quicker route through sustainable energy production.