The objective of the research is twofold. The study examines the role of public finance in promoting sustainable development in SSA. Secondly, the study investigates the optimal level of public finance beyond which public finance crowds out investment and hinders sustainable development in SSA. The study adopts a battery of econometric techniques such as the traditional ordinary least square (OLS) estimation technique, Driscoll-Kraay covariance matrix estimator, and the dynamic panel threshold model. The study found that an increase in public debts lead to a decline in sustainable development. In contrast, the results show that increase in spending on health and education, and tax can engender sustainable development in SSA. Further, we uncover the optimal levels of public spending on health and education, and public debts that engenders sustainable development in SSA. One main implication of the findings is that governments across SSA needs to reduce public debts levels and increase public spending on health and education to within the threshold levels established in this study to aid sustainable development in SSA.

This study investigates the evolution of monetary policy in Ghana and explores the potential of Central Bank Digital Currencies (CBDCs), specifically the e-Cedi, as a tool to enhance financial inclusion and modernize the country’s financial system. Ghana’s monetary policy framework has undergone significant transformations since the establishment of the Bank of Ghana in 1957, with notable achievements in stabilizing the economy and managing inflation. However, large segments of the population, particularly in rural areas, remain unbanked or underbanked, highlighting the limitations of traditional monetary tools. The introduction of the e-Cedi presents an opportunity to bridge these gaps by providing secure, efficient, and accessible financial services to underserved communities. The study employs a qualitative research design, integrating historical analysis, case studies, and thematic analysis to assess the potential benefits and challenges of CBDCs in Ghana. Key findings indicate that while the e-Cedi could significantly enhance financial inclusion, challenges related to technological infrastructure, cybersecurity, and public trust must be addressed. The study concludes that a balanced approach, which prioritizes digital infrastructure development, strong cybersecurity measures, and collaboration with financial institutions, is essential for maximizing the potential of CBDCs in Ghana. Recommendations for future research include a deeper exploration of the impact of CBDCs on financial stability and further analysis of rural adoption barriers.

Good health and well-being are embedded in the 3rd Goal amongst the UN Sustainable Development Goals. The primary objective of this research was to identify the most critical economic, social, and administrative barriers to implementing the Expanded Program on Immunization (EPI) in the Punjab Province of Pakistan. A sequential exploratory design and case study technique were used, employing both qualitative and quantitative methods. In the first stage, in-depth interviews with 50 key officials were conducted to identify the most critical barriers to the EPI program. A quantitative analysis was then performed based on the results obtained from qualitative analysis, and rank orders of barriers were received from the same health department experts. The results indicate that twenty-eight barriers can cause implementation problems for this program. Still, the ten barriers that gained the maximum hits are the most important barriers, which include Shortage of vaccinators, mismanagement of vaccines’ cold chain, biometric android application, ice-lined refrigerators, communication gap, inadequate legislation of EPI program, capacity building issues with EPI staff, Misconceptions about EPI program, lack of awareness of the parents and community, refusal cases and inadequate cooperation of lady health workers (LHWs). Coordinated efforts of the government and the public are highly recommended to address these barriers.

Using a Global Trade Analysis Project (GTAP) model, and China as the base for analytical comparison, this paper shows that there are significant economic benefits to China and the participating countries along all six Belt and Road Initiative (BRI) economic corridors. However, to maximize these benefits, the social and environmental risks need to be well managed. The analysis shows a clear sequencing in terms of priority corridors. Two corridors have minimal investments and immediate returns, two corridors have significant investments with huge returns, and two corridors have high investments with lower returns. Overall, the paper demonstrates that to ensure the sustainability of any BRI corridor development, there is a need to consider its costs and benefits from the economic, social and environmental perspectives.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.

The design of effective flood risk mitigation strategies and their subsequent implementation is crucial for sustainable development in mountain areas. The assessment of the dynamic evolution of flood risk is the pillar of any subsequent planning process that is targeted at a reduction of the expected adverse consequences of the hazard impact. This study focuses on riverbed cities, aiming to analyze flood occurrences and their influencing factors. Through an extensive literature review, five key criteria commonly associated with flood events were identified: slope height, distance from rivers, topographic index, and runoff height. Utilizing the network analysis process within Super Decision software, these factors were weighted, and a final flood risk map was generated using the simple weighted sum method. 75% of the data was used for training, and 25% of it was used for testing. Additionally, vegetation changes were assessed using Landsat imagery from 2000 and 2022 and the normalized difference vegetation index (NDVI). The focus of this research is Qirokarzin city as a case study of riverbed cities, situated in Fars province, with Qir city serving as its central hub. Key rivers in Qirokarzin city include the Qara Aghaj River, traversing the plain from north to south; the primary Mubarak Abad River, originating from the east; and the Dutulghaz River, which enters the eastern part of the plain from the southwest of Qir, contributing to plain nourishment during flood events. The innovation of this paper is that along with the objective to produce a reliable delineation of hazard zones, a functional distinction between the loading and the response system (LS and RS, respectively) is made. Results indicate the topographic index as the most influential criterion, delineating Qirokarzin city into five flood risk zones: very low, low, moderate, high, and very high. Notably, a substantial portion of Qirokarzin city (1849.8 square kilometers, 8.54% of the area) falls within high- to very-high flood risk zones. Weighting analysis reveals that the topographic humidity index and runoff height are the most influential criteria, with weights of 0.27 and 0.229, respectively. Conversely, the height criterion carries the least weight at 0.122. Notably, 46.7% of the study area exhibits high flood intensity, potentially attributed to variations in elevation and runoff height. Flood potential findings show that the middle class covers 32.3%, indicating moderate flood risk due to changes in elevation and runoff height. The low-level risk is observed sporadically from the east to the west of the study area, comprising 12.4%. Analysis of vegetation changes revealed a significant decline in forest and pasture cover despite agricultural and horticultural development, exacerbating flood susceptibility.