Fungi can be used to remove or degrade polluting compounds through a mycoremediation process. Sometimes even more efficiently than prokaryotes, they can therefore be used to combat pollution from non-biodegradable polymers. Cellulose acetate is a commonly used material in the manufacture of cigarette butts, so when discarded, it generates pollution. The fungus Pleurotus ostreatus has the ability to degrade cellulose acetate through the enzymes it secretes. The enzyme hydrolyzes the acetyl group of cellulose acetate, while cellulolytic enzymes degrade the cellulose backbone into sugars, polysaccharides, or cellobiose. In addition to cellulose acetate, this fungus is capable of degrading other conventionally non-biodegradable polymers, so it has the potential to be used to reduce pollution. Large-scale cultivation of the fungus has proven to be more economically viable than conventional methods for treating non-biodegradable polymers, which is an additional advantage.
Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myo-inositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistance-related protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (P < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (P > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (P < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FU-responsive ones at 5-FU concentrations greater than 2.5 μg/mL (P < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.
Liquid Metal Battery (LMB) technology is a new research area born from a different economic and political climate that has the ability to address the deficiencies of a society where electrical energy storage alternatives are lacking. The United States government has begun to fund scholarly research work at its top industrial and national laboratories. This was to develop Liquid Metal Battery cells for energy storage solutions. This research was encouraged during the Cold War battle for scientific superiority. Intensive research then drifted towards high-energy rechargeable batteries, which work better for automobiles and other applications. Intensive research has been carried out on the development of electrochemical rechargeable all-liquid energy storage batteries. The recent request for green energy transfer and storage for various applications, ranging from small-scale to large-scale power storage, has increased energy storage advancements and explorations. The criteria of high energy density, low cost, and extensive energy storage provision have been met through lithium-ion batteries, sodium-ion batteries, and Liquid Metal Battery development. The objective of this research is to establish that Liquid Metal Battery technology could provide research concepts that give projections of the probable electrode metals that could be harnessed for LMB development. Thus, at the end of this research, it was discovered that the parameter estimation of the Li//Cd-Sb combination is most viable for LMB production when compared with Li//Cd-Bi, Li-Bi, and Li-Cd constituents. This unique constituent of the LMB parameter estimation would yield a better outcome for LMB development.
This article analyses the case of Dubai’s smart city from a public policy perspective and demonstrates how critical it is to rely on the use of the public-private partnership (PPP) model. Effective use of this model can guarantee the building of a smart city that could potentially fulfill the vision of the political leadership in Dubai and serve as a catalyst and blueprint for other Gulf states that wish to follow Dubai’s example. This article argues that Dubai’s smart city project enjoys significant political support and has ambitious plans for sustainable growth, and that the government has invested heavily in developing the necessary institutional, legal/regulatory, and supervisory frameworks that are essential foundations for the success of any PPP project. The article also points to some important insights that the Dubai government can learn from the international experience with the delivery of smart cities through PPPs.
Bamboo is one of the noble plant species in Ethiopia. Household (HH) income and construction role of highland bamboo (Oldeania alpina (K. Schum.) Stapleto) stands were assessed at Masha district, Southern Ethiopia. Three peasant associations (PAs), Yepo, Yina and Gada, 7–15 key informants and 68, 46, 31 households, respectively were interviewed about the cost and income of bamboo to compare with woody climbers, honey, and mushroom in 2021. Bamboo was one of the main sources of income in all PAs, at least for fencing or house construction. In Yepo, Yina and Gada bamboo accounts 0.7%, 28.1%, 16.3% of the HH NTFP income, respectively. The local people responded that bamboo constructed houses and fences were durable for 15–30 and 2–10 years, respectively. In constructing a 2.44–4.27 m radius local house in Yepo, Yina and Gada 2.4–6 m3, 4.1–5.82 m3 and 3.1–4.3 m3 bamboo culms were harvested at 15, 20, and 30 years interval, respectively by each HH. Bamboo young shoots were also seasonally used for food. Although bamboo provides multiple uses, like substitute for wood and environmental services, it was facing different problems of deforestation. Therefore, policy attention is highly important for bamboo sustainable utilization.
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