Objective: To investigate the value of differential diagnosis of hepatocellular carcinoma (HCC) and cirrhotic nodules via radiomics models based on magnetic resonance images. Background: This study is to distinguish hepatocellular carcinoma and cirrhotic nodules using MR-radiomics features extracted from four different phases of MRI images, concluded T1WI, T2WI, T2 SPIR and delay phase of contrast MRI. Methods: In this study, the four kind of magnetic resonance images of 23 patients with hepatocellular carcinoma (HCC) were collected. Among them, 12 patients with liver cirrhosis were used to obtain cirrhotic nodules (CN). The dataset was used to extract MR-radiomics features from regions of interest (ROI). The statistical methods of MRradiomics features could distinguish HCC and CN. And the ability of radiomics features between HCC and CN was estimated by receiver operating characteristic curve (ROC). Results: A total of 424 radiomics features were extracted from four kind of magnetic resonance images. 86 features in delay phase of contrast MRI,86 features in spir phase of T2WI,86 features in T1WI and 88 features in T2WI showed statistical difference (p < 0.05). Among them, the area under the curves (AUC) of these features larger than 0.85 were 58 features in delay phase of contrast MRI, 54 features in spir phase of T2WI, 62 features in T1WI and 57 features in T2WI. Conclusions: Radiomics features extracted from MRI images have the potential to distinguish HCC and CN.
Flood risk analysis is the instrument by which floodplain and stormwater utility managers create strategic adaptation plans to reduce the likelihood of flood damages in their communities, but there is a need to develop a screening tool to analyze watersheds and identify areas that should be targeted and prioritized for mitigation measures. The authors developed a screening tool that combines readily available data on topography, groundwater, surface water, tidal information for coastal communities, soils, land use, and precipitation data. Using the outputs of the screening tool for various design storms, a means to identify and prioritize improvements to be funded with scarce capital funds was developed, which combines the likelihood of flooding from the screening tool with a consequence of flooding assessment based on land use and parcel size. This framework appears to be viable across cities that may be inundated with water due to sea-level rise, rainfall, runoff upstream, and other natural events. The framework was applied to two communities using the 1-day 100-year storm event: one in southeast Broward County with an existing capital plan and one inland community with no capital plan.
The augmentation of firm performance via customer concentration is particularly indispensable for organizational evolution. Both trade credit financing and financing constraints play pivotal roles in the nexus between customer concentration and performance. This research constructs a moderated mediation model to rigorously investigate the impact of customer concentration on firm performance, positing trade credit financing as the mediating variable and financing constraints as the moderating variable. The relevant hypotheses are evaluated empirically using panel data compiled from listed manufacturing firms in China over the period 2013–2020, yielding 8 firm-year observations. The empirical outcomes denote that customer concentration exerts a positive influence on firm performance, albeit having a negative impact on trade credit financing. Trade credit financing serves as a partial mediator in the relationship between customer concentration and manufacturing firm performance. Financing constraints are found to positively moderate the mediating role of trade credit financing in the relationship between customer concentration and firm performance. This research broadens the understanding of the implications of customer relationships on trade credit financing and performance, thereby enriching the knowledge base for managing a firm’s financing channels more effectively.
This study aims to examine the impact of an innovative self-directed professional development (SDPD) model on fostering teachers’ professional development and improving their ability to manage this development independently. A quantitative research method was adopted, involving 60 participants from Almaty State Humanitarian and Pedagogical College No. 2, Almaty, Kazakhstan. Descriptive and inferential statistics were used to assess the SDPD model’s effectiveness, specifically in promoting teacher engagement, adoption of new pedagogical techniques, and improvement in reflective practices. The study findings reveal that teachers, particularly in developing regions, often face challenges in accessing formal professional development programs. The implementation of the SDPD model addresses these barriers by providing teachers with the tools and strategies required for self-improvement, regardless of geographic or economic constraints. The study participants in the pilot phase showed increased engagement with new pedagogical methods, improved reflective practices, and greater adaptability to emerging educational technologies. The algorithmic aspect of the model streamlined the professional development process, while the activity-based approach ensured that learning remained practical and relevant to teachers’ everyday needs. By offering a clear framework for continuous improvement, the model addresses the gaps in formal training access and cultivates a culture of lifelong learning. These findings suggest that the SDPD model can contribute to elevating teaching standards globally, particularly in regions with limited professional development resources.
This study examines the bottleneck effect of logistics performance on Vietnam’s imports, utilizing bilateral trade data from 2007 to 2022. We evaluate the impact of logistics performance on imports of Vietnam using the augmented gravity model and a random effects estimator. Our findings reveal that the minimum logistics performance between Vietnam and its trading partners has a significantly positive impact on the Vietnamese imports. The magnitude of its bottleneck effects is much larger than the influence of Vietnam’s individual logistics performance or deviations in performance with its trading partners. Recognizing the impact of logistics bottlenecks on international trade enables policymakers to develop more effective and efficient logistics-related policies for enhancing bilateral trade with trading partners.
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