Leukemia is a major public health problem in China, but epidemiological studies on leukemia in China are still insufficient. This study aims to analyze leukemia's disease burden and risk factors in China from 2010 to 2021 and provide a basis for leukemia prevention and treatment. Using data from the Global Burden of Disease (GBD) database, trends in the burden of leukemia in China from 2010 to 2021 were analyzed. Additionally, epidemiological differences by gender and age groups were explored. In 2021, there were 531,000 leukemia patients in China, with 106,000 new cases and 59,000 deaths. Compared to 2010, the mortality rate and disability-adjusted life years (DALYs) per 100,000 population in 2021 decreased by 5% and 18%, respectively, while the incidence and prevalence rates increased by 12% and 29%, respectively. Gender and age stratification indicated that males had higher rates across all indicators than females, and elderly individuals faced higher leukemia mortality and DALYs. The most significant decrease in DALYs was observed in children and adolescents under 20. The highest burden of leukemia for males was found in the 85–90 age group, while for females, it was in the 70–74 age group. Major risk factors for leukemia included smoking, high BMI, and exposure to carcinogens, benzene, and formaldehyde. The overall burden of leukemia in China showed a decreasing trend, with significant gender and age differences. More measures are needed to reduce leukemia mortality, particularly focusing on the prevention and treatment of leukemia in males and the elderly.
Background: Through the development of robust techniques and their comprehensive validation, cardiac magnetic resonance imaging (CMR) has developed a wide range of indications in its almost 25 years of clinical use. The recording of cardiac volumes and systolic ventricular function as well as the characterization of focal myocardial scars are now part of standard CMR imaging. Recently, the introduction of accelerated image acquisition technologies, the new imaging methods of myocardial T1 and T2 mapping and 4-D flow measurements, and the new post-processing technique of myocardial feature tracking have gained relevance. Method: This overview is based on a comprehensive literature search in the PubMed database on new CMR techniques and their clinical application. Results and conclusion: This article provides an overview of the latest technical developments in the field of CMR and their possible applications based on the most important clinical questions.
As the technical support for economic activities and social development, standards play a great role in modern society. However, with the increasing digitization of various industries, the traditional form of standards can no longer meet the needs of the new era, and there is an urgent need to digitally transform standards using advanced technologies. The digital transformation of standards involves the standard itself and all stages of its life cycle, is a very complex systematic project, in the transformation process, technology plays a key role. Therefore, this paper summarizes the key technologies involved in the process of digital transformation of standards, sorted out and evaluated them according to different purposes for which they were used, while giving the digitalization of standards transformation technology development trends and planning as well as typical cases, hoping to provide a comprehensive and clear perspective for those engaged in the related work, as well as reference for the subsequent research and application of digital transformation of standards.
The article is dedicated to analyzing trends in the development of startup infrastructure in Ukraine, Latvia and Georgia. The article is based on concrete data, a comprehensive analysis of statistical and qualitative data on the development of startups in Ukraine, Latvia and Georgia. This provides a reliable basis for the arguments and conclusions. General patterns of startup infrastructure development in the three countries were identified. A PEST analysis of startup infrastructure development in Ukraine, Latvia and Georgia was conducted. Thus, the authors conduct a multidisciplinary analysis that includes not only economic, but also social and technological aspects of startup ecosystems and infrastructures. Suggestions for improving the startup infrastructure in these countries were developed.
This study delves into the dynamic landscape of pension funds in Colombia, examining both its current research status and practical implications. Understanding the state of pension systems is crucial for individuals' financial security and a country's overall economic stability, especially given factors such as an aging population and evolving socio-economic dynamics. By comprehensively analyzing scholarly publications on Colombian pension funds using the Scopus database, this research sheds light on key trends and contributors shaping policy formulation and financial planning. The analysis covers a period from 1987 to 2023, identifying 71 relevant articles through keyword searches and filters. Various metrics, including publication trends, citations, international collaboration, and authorship dynamics, were quantitatively assessed. The results reveal an annual growth rate of 5.37%, with research articles comprising 81.69%, review articles 7.04%, and other formats like books, book chapters, and conference papers making up 11.27% of the total documents. Notably, countries such as the UK, the USA, Spain, and Colombia emerge as key contributors to the literature. Among authors, Mesa-Lago, L., stands out as a significant figure, with one of the earliest publications on the topic. The findings underscore the growing importance of pension funds in Colombia, particularly in the context of fund performance research amid financial crises. The prevalence of international collaboration suggests a global interest in understanding and contributing to the development of Colombian pension systems. Furthermore, the study identifies research gaps, particularly in areas concerning the socio-economic impact of pension policies, providing a roadmap for future investigations. Policymakers, financial practitioners, and researchers can leverage these insights to inform strategic decision-making and address critical challenges in optimizing pension fund management in Colombia.
Objective/Aim: In the context of a constantly changing legislative environment and the necessity for professionals to develop their skills, the research focuses on identifying effective methods and tools that facilitate efficient learning and professional development in the field of labour law. This study aimed to propose a pedagogical technology for the preparation and training of specialists in the field of labour law and to assess the effectiveness of the training based on the specified technology. Method: The study involved 124 participants, with 63 in the experimental group and 61 in the control group. Statistical analysis was performed using Microsoft Excel. The student’s t-test indicated significant improvements in the experimental group’s training effectiveness, confirming the proposed pedagogical technology’s efficacy. Results: Consequently, implementing training and education technology for specialists in the labour law field was proposed to enhance the indicators. The criteria for the preparation of specialists in the field of labour law were delineated, including knowledge of labour legislation, consulting and support skills, analytical skills, communication skills, and continuous learning. According to the criteria above, levels of preparation for specialists in the field of labour law were established, namely high, medium, and essential. The proposed training and education technology for specialists in the field of labour encompasses the following tools: The utilisation of online platforms and educational resources, virtual classes and simulations, the incorporation of multimedia materials, the integration of adaptive learning technologies, the implementation of project- and problem-oriented teaching methodologies, the incorporation of interactive methodologies, the incorporation of cloud technologies and mobile applications, and the provision of assessment and feedback. Conclusion: The proposed pedagogical technology effectively enhances the training and education of labour law specialists. The experimental group’s significant improvement in learning outcomes confirms the technology’s efficacy. Implication: The findings of this research hold significant social implications. Improved training and education of labour law specialists leads to a more competent and effective legal workforce. This, in turn, ensures better protection of workers’ rights and fairer employer-employee relations, contributing to overall social stability.
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