5G technology is transforming healthcare by enhancing precision, efficiency, and connectivity in diagnostics, treatments, and remote monitoring. Its integration with AI and IoT is set to revolutionize healthcare standards. This study aims to establish the state of the art in research on 5G technology and its impact on healthcare innovation. A systematic review of 79 papers from digital libraries such as IEEE Xplore, Scopus, Springer, ScienceDirect, and ResearchGate was conducted, covering publications from 2018 to 2024. Among the reviewed papers, China and India emerge as leaders in 5G health-related publications. Scopus, Springer Link, and IEEE Xplore house the majority of first-quartile (Q1) papers, whereas Science Direct and other sources show a higher proportion in the second quartile (Q2) and lower rankings. The predominance of Q1 papers in Scopus, Springer Link, and IEEE Xplore underscores these platforms’ influence and recognition, reflecting significant advancements in both practice and theory, and highlighting the expanding application of 5G technology in healthcare.

Technological advancements in genetic research are crucial for nations aiming to uplift their population’s quality of life and ensure a sustainable economy. Genomic information and biotechnology can enhance healthcare quality, outcomes, and affordability. The “P4 medicine approach”—predictive, preventive, personalized, and participatory—aligns with objectives like promoting long-term well-being, optimizing resources, and reducing environmental impacts, all vital for sustainable healthcare. This paper highlights the importance of adopting the P4 approach extensively. It emphasizes the need to enhance healthcare operations in real-time and integrate cutting-edge genomic technologies. Eco-friendly designs can significantly reduce the environmental impact of healthcare. Additionally, addressing health disparities is crucial for successful healthcare reforms.

This paper tries to understand economic, social and legal implications of the introduction and usage of MediSearch (AI search engine) in the Indian healthcare context. Discussing the economic ramifications, the paper highlights the potential for cost savings, the influence on healthcare accessibility, and the shifts in traditional medical paradigms. On the social side, the study explains ability of AI based platforms to bridge healthcare disparities, with a potential for enhancing general health literacy among the general population. From a legal standpoint, study highlights the concerns related to data privacy, regulatory issues, and possible malpractice implications. With the integration of these perspectives, the study also explains opportunities, challenges and future of MediSearch from the Indian health perspective.