There are numerous studies reported on the usage of the sapindus emarginatus (SE) fruit in cancer and other treatments in the past few years. In this study, crude SE fruit extract was prepared and it was further used to synthesis gold nanoparticles (Au Nps). The synthesized Au Nps were left embedded in the SE fruit extract. The Au Nps embedded in the SE fruit extract (SE-Au Nps) were characterized using UV-Visiable Spectroscopy, Centrifugal Particle Size analyzer (CPS), Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). MTT assay was carried out for both SE fruit extract and SE-Au Nps on MCF7 breast cancer cell line and thus compared. The UV-Visible Absorbance for the SE-Au Nps was obtained at 543 nm. The centrifugal particle size analysis of the Au Nps embedded in SE fruit extract showed the size of the nanoparticles to be widely varying with higher fraction of particles between the size ranges of 15 to 20 nm. The morphology of the Au Nps embedded in SE fruit extract was observed using SEM. The presence of Au Nps in SE fruit extract was confirmed using FTIR. The results of the MTT assay on MCF7 breast cancer cell line proved that the % cell viability was less for SE-Au Nps than that of the SE fruit extract alone. Thus, the antiproliferative activity of the SE fruit extract was significantly enhanced by embedding it with Au Nps and it can be effectively used in therapeutic applications after further studies.

In the present study, friction damper, an energy dissipating passive device is explored to reduce the response of open ground storey building under lateral loading due to earthquake. This damper is installed in the selected bays of open ground storey so that the response is reduced. The masonry infill wall is macro-modeled in the form of compression only diagonal members. Three different types of bracing system were installed along with Pall friction damper – single diagonal tension – compression brace with friction damper, tension only cross brace with friction damper and chevron brace with friction damper were modeled using Wen’s plastic link element in SAP2000. G+4 storey buildings were analyzed using nonlinear time history analysis. The storey displacement and inter-storey drift for all the cases were compared in the study.

Purpose: This paper articulates a model that maximizes the use of e-HRM to achieve sustainable competitive advantage. It examines the indirect effects of e-HRM use on sustainable competitive advantage, through job satisfaction, employee performance, and perceived organizational politics. Design/methodology/approach: A survey approach was used to collect data from 30 organizations. A purposive sampling technique was used to select the study sample. The SPSS PROCESS Macro for running mediation analysis was used to analyze data. Findings: The findings show the indirect effect of e-HRM on sustainable competitive advantage through job satisfaction, employee performance, and perceived organizational politics. Job satisfaction has the biggest effect on achieving strategic outcomes. For organizational excellence, e-HRM use should complement other HRM practices. Practical implications: Management should pay attention to employee outcomes during the implementation of e-HRM. This study broadens the scope of the interaction between e-HRM use and sustainable competitive advantage. This study was conducted in a developing economy and demonstrated that the effects of e-HRM use on sustainable competitive advantage are not limited to developed economies. Originality/value: This study is one of the pioneering efforts to develop a model that maximizes organizational outcomes in developing countries. In addition, this study contributes to the understanding of intervening variables necessary to enhance information technology’s potential within the HR function.

Objective: To evaluate the imaging features of spondyloarthritis on magnetic resonance imaging (MRI) of the sacroiliac (SI) joints in terms of topography (in thirds) and affected margin, since this aspect is rarely addressed in the literature. Methods: Cross-sectional study with MRI (1.5 T) evaluation of the SI in 16 patients with diagnosis of axial spondyloarthritis regarding the presence of acute (subchondral bone edema, enthesitis, synovitis and capsulitis) and chronic changes (erosions, subchondral bone sclerosis, bone bridging and fatty replacement), performed by two radiologists, blinded to clinical data. MRI findings were correlated with clinical data including age, disease duration, medications, HLA-B27, BASDAI, ASDAS-VHS and ASDAS-PCR, BASMI, BASFI, and mSASSS. Results: Bone edema pattern and erosions showed predominance in the upper third of SI (p = 0.050, p = 0.0014, respectively). There was a correlation between the time of disease and structural changes by affected third (p = 0.028-0.037), as well as the presence of bone bridges with BASMI (p = 0.028) and mSASSS (p = 0.014). Patients with osteitis of the lower third had higher ASDAS values (ESRV: p = 0.011 and CRP: p = 0.017). Conclusion: Chronic inflammatory changes and the pattern of bone edema predominated in the upper third of the SI, but there was also concomitant involvement of the middle or lower thirds of the joint. The localization of involvement in the upper third of the SI was insufficient to differentiate between degeneration and inflammation.

This exploratory study aims to identify the main characteristics and relationships between artificial intelligence (AI) and broadband development in Asia and the Pacific. Broadband networks are the foundation and prerequisite for the development of AI. But what types of broadband networks would be conducive are not adequately discussed so far. Furthermore, in addition to broadband networks, other factors, such as income level, broadband quality, and investment, are expected to influence the uptake of AI in the region. The findings are synthesized into a set of policy recommendations at the end of the article, which highlights the need for regional cooperation through an initiative, such as the Asia-Pacific Information Superhighway (AP-IS). 

The article examines the current state of fertility processes in Kazakhstan, the diversity of reproductive scenarios, and the reasons for their formation. The authors proceed by analysing the sovereign demographic system formed in Kazakhstan in the first quarter of the 21st century based on the Kazakh ethnic group. Cluster analysis was performed for demographic zones, considering indicators such as the proportion of Kazakhs in the urban population and the total fertility rate in cities. We believe that case technology allows us to demonstrate the differences in the reproductive attitudes and behaviour of urban Kazakhs, ultimately determining the trends in reproductive processes in the country. The focus is given to the socio-cultural and socio-economic differences across the regions of Kazakhstan and their impact on fertility processes in the context of the accelerated urbanisation of Kazakhs. The main variants of adaptation of the reproductive behaviour of Kazakhs to new urban living conditions are described, and an assumption is made about further prospects for maintaining or changing birth rates in Kazakhstan.