This article analyses the complex factors contributing to rising medical expenses, focusing on the senior citizen demographic in Malaysia. With the global aging population, notably in lower and middle-income countries, the study highlights the escalating medical and health insurance costs, driven by age, income source, modern healthcare, and geographical residence. The research draws on an extensive literature review, demographic analysis, and quantitative methods to examine these determinants. It critically analyzes Malaysia’s healthcare system, which operates on a dual-tier model, and the financial burden placed on senior citizens. The findings indicate that age, source of income, and geographical residence significantly influence medical expenses, whereas modern healthcare’s impact is not statistically significant. The study calls for government intervention, insurance industry adjustments, and private sector support to mitigate the financial strain on senior citizens. Recommendations include tax relief adjustments, National Health Insurance Scheme implementation, and employment sustainability for seniors. This research provides some recommendations to policymaking, the insurance industry, and academia by providing insights into managing the healthcare needs of an aging population sustainably.

The main objective of this study is to identify the impact of trust on the construction of corporate value in commerce and services microbusinesses. This work is based on identifying the challenges faced by SMEs (Small and Medium-sized Enterprises), which are conditioned by the type of business and the regulatory and incentive variables that exist in the territory, affecting their permanence and stability in the market and their financial and commercial development. A local study is carried out in Bogotá, Colombia, through a descriptive research project, using a quantitative analysis method (SPSS) to process data obtained from local microbusinesses. As a result, it was observed that trust has a discrete impact on the creation of corporate value, which is created from the use of ICT (Information and Communication Technology). This leads to the recognition that it is necessary to strengthen horizontal networks with suppliers, clients, and similar businesses, as well as vertical networks with entities and public associations, to generate lasting and strong links that increase the competitiveness of these business units in the face of exogenous risks shaped by the social, economic, and cultural characteristics of the territory, which are increasingly conditioned to the use of communication technology.

According to the World Health Organization (WHO), breast cancer is among the most common cancers worldwide. Most of the anticancer agents have been showing a variety of side effects. Recently, bacterial proteins have been investigated as promising anticancer agents. Azurin is a bacterial cupredoxin protein secreted from Pseudomonas aeruginosa and has been reported as a potent multi-targeting anticancer agent, which makes it an appropriate candidate for drug delivery. Azurin may be delivered to cancer cells using different carriers like polymeric micro and nanoparticles. In the present study, azurin was extracted from the bacterial host and loaded into chitosan particles. Then its effect on MCF-7 cell line was investigated. Chitosan-azurin particles were made using the ion gelation method. Results showed that chitosan-azurin particles are about 200 nm, and the loading of the protein in particles did not affect its integrity. The MTT assay showed a significant reduction in cell viability in azurin and chitosan-azurin-treated cells. The toxicity level after 5 days was 63.78% and 82.53% for free azurin and chitosan-azurin-treated cells, respectively. It seems using an appropriate carrier system for anticancer proteins like azurin is a promising tool for developing low side effect anticancer agents.

Organomineral fertilizer is used to improve and ameliorate the supply of nutrients in soils. Right and adequate application of fertilizers are determinants of its nutrient supply efficiency, which in turn enhances the vegetative growth and yield of cucumber. Field experiments were conducted at the Research Farm of the Federal University of Agriculture, Abeokuta, Nigeria, to assess the effects of variety and rate of organomineral fertilizer on cucumber growth and yield. Trials were conducted from June to August 2019 and repeated from September to November 2019. The cultivars were Poinsett, Greengo, and Monalisa. The rates of organomineral fertilizer were 0, 2.5, or 5.0 tons. ha⁻¹. The treatments were replicated three times. Cucumber vegetative characters, yield, and yield components were studied. ‘Greengo’ produced the most leaves, followed by ‘Monalisa’; ‘Poinsett’ produced the least. Application of 5.0 tons. ha⁻¹ organomineral fertilizer produced the longest vines and fruits. ‘Greengo’ had the earliest days to 50% flowering, followed by ‘Monalisa’; ‘Poinsett’ had the most days to 50% flowering. Plants treated with an application of 5.0 tons. ha⁻¹ organomineral fertilizer attained 50% flowering in 29 days, but in 30 days with an application of 2.5 tons. ha⁻¹ organomineral fertilizer; the control treatment attained 50% flowering in 33 days. Application of 5.0 tons. ha⁻¹ organomineral fertilizer produced the longest fruits, thicker fruit diameter, and highest fruit yield compared with 2.5 and 0 tons. ha⁻¹ of organomineral fertilizer treatments. The Greengo variety with application of 5.0 tons. ha⁻¹ of organomineral fertilizer is recommended for optimum growth and yield in south western Nigeria.

This study aims to explore the implications of imported electrical equipment in Indonesia, analysing both short-term and long-term impacts using a quantitative approach. The research focuses on understanding how various economic factors, such as domestic production, international pricing, national income, and exchange rates, influence the country’s import dynamics in the electrical equipment sector. Employing an Error Correction Model (ECM) for regression analysis, the study utilises time-series data from 2007 to 2021 to delve into the complex interplay of these variables. The methodology involves a comprehensive analysis using the Augmented Dickey-Fuller and Phillips-Perron tests to assess the stationarity of the data. This approach ensures the robustness of the ECM, which is employed to analyse the short-term and long-term effects of the identified variables on electrical equipment imports in Indonesia. The results reveal significant relationships between these economic factors and import levels. In the short term, imports are shown to be sensitive to changes in domestic economic conditions and international market prices, while in the long term, the country’s economic growth, reflected through GDP, emerges as a significant determinant. The findings suggest that Indonesia’s electrical equipment import policies must adapt highly to domestic and international economic changes. In the short term, a responsive approach is required to manage the immediate impacts of market fluctuations. The study highlights the importance of aligning import strategies with broader economic growth and environmental sustainability goals for long-term sustainability. Policymakers are advised to focus on enhancing domestic production capabilities, reducing import dependency, and ensuring that environmental considerations are integral to import policies. This study contributes to understanding import dynamics in a developing country context, offering valuable insights for policymakers and industry stakeholders in shaping strategies for economic growth and sustainability in the electrical equipment sector. The findings underscore the need for a balanced, data-driven approach to managing imports, aligning short-term responses with long-term strategic objectives for Indonesia’s ongoing development and industrial advancement.

Managing business development related to the innovation of intelligent supply chains is an important task for many companies in the modern world. The study of management mechanisms, their content and interrelations of elements contributes to the optimization of business processes and improvement of efficiency. This article examines the experience of China in the context of the implementation of intelligent supply chains. The study uses the methods of thematic search and systematic literature review. The purpose of the article is to analyze current views on intelligent supply chain management and identify effective business management practices in this area. The analysis included publications devoted to various aspects of supply chain management, innovation, and the implementation of digital technologies. The main findings of the article are as follows: Firstly, the key elements of intelligent supply chain management mechanisms are identified, secondly, successful experiences are summarized and the main challenges that companies face in their implementation are identified. In addition, the article focuses on the gaps in research related to the analysis of successful experiences and the reasons for achieving them.